Afraxis (United States)

Rescue of fragile X syndrome phenotypes in <i>Fmr1</i> KO mice by the small-molecule PAK inhibitor FRAX486

Bridget Dolan, Sergio G. Durón, David A. Campbell et al. · Proceedings of the National Academy of Sciences · 2013 · 275 citations · Full text

REDD1 is essential for stress-induced synaptic loss and depressive behavior

Kristie T. Ota, Rong-Jian Liu, Bhavya Voleti et al. · Nature Medicine · 2014 · 265 citations · Full text

Synaptic Plasticity, Psychiatry, Behavioral Neuroscience +7

p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model

Hoi Yee Chow, Adrian M. Jubb, Jennifer N. Koch et al. · Cancer Research · 2012 · 160 citations · Full text

Tumor Regression, Ras Genes, Dermatology +17

FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas

Silvia Licciulli, Jasna Maksimoska, Chun Zhou et al. · Journal of Biological Chemistry · 2013 · 127 citations · Full text

Modeling consequences of prolonged strong unpredictable stress in zebrafish: Complex effects on behavior and physiology

Cai Song, Bai-Ping Liu, Yongping Zhang et al. · Progress in Neuro-Psychopharmacology and Biological Psychiatry · 2017 · 113 citations

Biology, Health Sciences, Behavioral Plasticity +11