Telesta Therapeutics (Canada)

CCNE1 amplification is synthetic lethal with PKMYT1 kinase inhibition

David Gallo, Jordan T.F. Young, Jimmy Fourtounis et al. · Nature · 2022 · 229 citations · Full text

Life Sciences, Genetics, Oncology +17

The CIP2A–TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer

Salomé Adam, Silvia Emma Rossi, Nathalie Moatti et al. · Nature Cancer · 2021 · 120 citations

Life Sciences, Genetics, Molecular Biology +13

Efficacy of Mycobacterium Phlei Cell Wall-Nucleic Acid Complex (MCNA) in BCG-Unresponsive Patients

Roger Li, John Amrhein, Zvi R. Cohen et al. · Bladder Cancer · 2016 · 36 citations · Full text

Medicine, Internal Medicine, Oncology +13

Discovery of the Potent and Selective ATR Inhibitor Camonsertib (RP-3500)

W. Cameron Black, Abbas Abdoli, Xiuli An et al. · Journal of Medicinal Chemistry · 2024 · 27 citations · Full text

Medicine, Oncology, Pharmacology +15

CCNE1 amplification is synthetic-lethal with PKMYT1 kinase inhibition

David Gallo, Jordan T.F. Young, Jimmy Fourtounis et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 22 citations · Full text

Life Sciences, Cancer Biology, Oncology +17