APIM Therapeutics (Norway)

Targeting Proliferating Cell Nuclear Antigen and Its Protein Interactions Induces Apoptosis in Multiple Myeloma Cells

Rebekka Müller, Kristine Misund, Toril Holien et al. · PLoS ONE · 2013 · 101 citations · Full text

Cell Nuclear Antigen, Apoptosis, Immunology +13

“Two hits - one stone”; increased efficacy of cisplatin-based therapies by targeting PCNA’s role in both DNA repair and cellular signaling

Caroline Krogh Søgaard, Augun Blindheim, Lisa Marie Røst et al. · Oncotarget · 2018 · 46 citations · Full text

Genome Instability, Urology, Apim-peptide Hits +15

Increased Anticancer Efficacy of Intravesical Mitomycin C Therapy when Combined with a PCNA Targeting Peptide

Odrun A. Gederaas, Caroline D. Søgaard, Trond Viset et al. · Translational Oncology · 2014 · 41 citations · Full text

APIM-peptide targeting PCNA improves the efficacy of docetaxel treatment in the TRAMP mouse model of prostate cancer

Caroline Krogh Søgaard, Siver Andreas Moestue, Morten Beck Rye et al. · Oncotarget · 2018 · 39 citations · Full text

ATX-101, a Peptide Targeting PCNA, Has Antitumor Efficacy Alone or in Combination with Radiotherapy in Murine Models of Human Glioblastoma

Giovanni Luca Gravina, Alessandro Colapietro, A. Mancini et al. · Cancers · 2022 · 26 citations · Full text

Cell Cycle, High-grade Gliomas, Cancer Biology +19