Concepedia

Zona Pellucida Changes

Zona Pellucida Changes is a structural alteration in the glycoprotein layer surrounding the oocyte or embryo characterized by increased rigidity and reduced elasticity induced during slow freezing protocols, which distinguishes it from other cryopreservation-induced cellular effects by specifically impairing blastocyst hatching and implantation potential.

285

Publications

14.2K

Citations

1K

Authors

381

Institutions

Publications per year

2017–2026

14

Parents

Publications

285

Freeze–thaw-induced changes of the zona pellucida explains decreased rates of fertilization in frozen–thawed mouse oocytes

John Carroll, Herman Depypere, Colin D. Matthews · Reproduction · 1990 · 227 citations · Full text

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Retention of Biologic Characteristics of Zona Pellucida in Highly Concentrated Salt Solution: The Use of Salt-Stored Eggs for Assessing the Fertilizing Capacity of Spermatozoa

Ryuzo Yanagimachi, Charles B. Odom, Richard Bronson et al. · Fertility and Sterility · 1979 · 222 citations

, , +16

The hardening effect of dimethylsulphoxide on the mouse zona pellucida requires the presence of an oocyte and is associated with a reduction in the number of cortical granules present

Caroline Vincent, Susan J. Pickering, Martin H. Johnson · Reproduction · 1990 · 220 citations · Full text

, , +12

Calcium-free vitrification reduces cryoprotectant-induced zona pellucida hardening and increases fertilization rates in mouse oocytes

Mark G. Larman, C. Sheehan, David K. Gardner · Reproduction · 2005 · 218 citations

, , +15

Mammalian sperm-egg interaction: Fertilization of mouse eggs triggers modification of the major zona pellucida glycoprotein, ZP2

Jeffrey D. Bleil, Clifford F. Beall, Paul M. Wassarman · Developmental Biology · 1981 · 213 citations

, , +16

1–5 of 285

Authors

1K

  1. RM
    Richard M. Schultz

    University of Pennsylvania, United States

    9 publications · 726 citations

    9

    h-index

  2. GS
    Gregory S. Kopf

    University of Pennsylvania, United States

    9 publications · 726 citations

    9

    h-index

  3. MA
    Manuel Avilés

    Universidad de Murcia, Spain

    8 publications · 347 citations

    8

    h-index

  4. TD
    Tom Ducibella

    Tufts University, United States

    5 publications · 393 citations

    5

    h-index

  5. MH
    Martin H. Johnson

    University of Cambridge, United Kingdom

    5 publications · 413 citations

    5

    h-index

1–5 of 1K

Institutions

381

  1. University of Pennsylvania

    Philadelphia, United States

    15 h-index

    40 publications

    2.8K citations

  2. Universidad de Murcia

    Murcia, Spain

    9 h-index

    40 publications

    1.3K citations

  3. Tel Aviv University

    Tel Aviv, Israel

    7 h-index

    15 publications

    319 citations

  4. Cornell University

    Ithaca, United States

    7 h-index

    20 publications

    1.3K citations

  5. Sapienza University of Rome

    Rome, Italy

    6 h-index

    16 publications

    830 citations

  6. University of Cambridge

    Cambridge, United Kingdom

    6 h-index

    13 publications

    1.1K citations

  7. Royal Women's Hospital

    Melbourne, Australia

    4 h-index

    8 publications

    316 citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    14 publications

    996 citations

1–8 of 381

Venues

  1. Human Reproduction

    29 publications · 2K citations

    25

    h-index

  2. Biology of Reproduction

    25 publications · 1.4K citations

    24

    h-index

  3. Reproduction

    30 publications · 2.1K citations

    22

    h-index

  4. Fertility and Sterility

    17 publications · 879 citations

    15

    h-index

  5. Molecular Reproduction and Development

    16 publications · 528 citations

    13

    h-index

1–5