Concepedia

Within-host Pathogen Evolution

Within-Host Pathogen Evolution is a theoretical framework in evolutionary epidemiology that characterizes the dynamic genetic and phenotypic changes of pathogens occurring within individual hosts during infection, distinguishing it from population-level transmission dynamics by focusing on selective pressures, mutation rates, and host immune interactions at the intrahost scale.

59

Publications

3.6K

Citations

340

Authors

183

Institutions

Publications per year

2017–2026

28

Parents

Publications

59

Host Species Barriers to Influenza Virus Infections

Thijs Kuiken, Edward C. Holmes, John W. McCauley et al. · Science · 2006 · 475 citations

, , +16

Environmental Heterogeneity Drives Within-Host Diversification and Evolution of Pseudomonas aeruginosa

Trine Markussen, Rasmus L. Marvig, María Gómez‐Lozano et al. · mBio · 2014 · 182 citations · Full text

, , +17

PHYLOSCANNER: Inferring Transmission from Within- and Between-Host Pathogen Genetic Diversity

Chris Wymant, Matthew Hall, Oliver Ratmann et al. · Molecular Biology and Evolution · 2017 · 182 citations · Full text

, , +17

Within-host evolution of a gut pathobiont facilitates liver translocation

Yi Yang, Mytien Nguyen, Varnica Khetrapal et al. · Nature · 2022 · 162 citations · Full text

, , +16

Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance

Stefany Moreno-Gámez, Alison L. Hill, Daniel I. S. Rosenbloom et al. · Proceedings of the National Academy of Sciences · 2015 · 156 citations · Full text

, , +17

1–5 of 59

Authors

340

  1. PK
    Paul Keim

    Northern Arizona University, United States

    3 publications · 217 citations

    3

    h-index

  2. DS
    Derek S. Sarovich

    Menzies School of Health Research, Australia

    3 publications · 275 citations

    3

    h-index

  3. RL
    Rasmus L. Marvig

    Rigshospitalet, Denmark

    3 publications · 337 citations

    3

    h-index

  4. TJ
    Timothy J. Kidd

    The University of Queensland, Australia

    3 publications · 314 citations

    3

    h-index

  5. SM
    Søren Molin

    Technical University of Denmark, Denmark

    3 publications · 337 citations

    3

    h-index

1–5 of 340

Institutions

183

  1. University of Cambridge

    Cambridge, United Kingdom

    7 h-index

    8 publications

    543 citations

  2. National Institutes of Health

    Bethesda, United States

    6 h-index

    14 publications

    3.4K citations

  3. University of Oxford

    Oxford, United Kingdom

    6 h-index

    21 publications

    1.9K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    32 publications

    711 citations

  5. Fogarty International Center

    Bethesda, United States

    4 h-index

    12 publications

    3.3K citations

  6. Pennsylvania State University

    State College, United States

    4 h-index

    10 publications

    3.1K citations

  7. Imperial College London

    London, United Kingdom

    4 h-index

    12 publications

    941 citations

  8. Technical University of Denmark

    Kongens Lyngby, Denmark

    4 h-index

    12 publications

    1.5K citations

1–8 of 183

Venues

  1. The American Naturalist

    AN · 5 publications · 225 citations

    5

    h-index

  2. Scientific Reports

    5 publications · 158 citations

    5

    h-index

  3. mBio

    5 publications · 437 citations

    5

    h-index

  4. Molecular Biology and Evolution

    MBE · 4 publications · 352 citations

    4

    h-index

  5. Evolution

    3 publications · 201 citations

    3

    h-index

1–5