Concepedia

Wapl Regulation

Wapl Regulation is a molecular mechanism within the broader category of chromosomal regulatory processes that specifically governs the removal of cohesin from chromatin by promoting the opening of the cohesin ring in a manner dependent on the Wapl protein.

53

Publications

7.7K

Citations

337

Authors

123

Institutions

Publications per year

2017–2026

23

Parents

Publications

53

Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins

Gordana Wutz, Csilla Várnai, Kota Nagasaka et al. · The EMBO Journal · 2017 · 925 citations · Full text

, , +14

Wapl Controls the Dynamic Association of Cohesin with Chromatin

Stephanie Kueng, Björn Hegemann, Beate H. Peters et al. · Cell · 2006 · 662 citations · Full text

, , +12

Eco1-Dependent Cohesin Acetylation During Establishment of Sister Chromatid Cohesion

Tom Rolef Ben-Shahar, Sebastian Heeger, Chris Lehane et al. · Science · 2008 · 533 citations

, , +17

Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl

Georg Busslinger, Roman R. Stocsits, Petra van der Lelij et al. · Nature · 2017 · 514 citations · Full text

, , +7

Human Wapl Is a Cohesin-Binding Protein that Promotes Sister-Chromatid Resolution in Mitotic Prophase

Rita Gandhi, Peter J. Gillespie, Tatsuya Hirano · Current Biology · 2006 · 460 citations · Full text

, , +15

1–5 of 53

Authors

337

  1. JP
    Jan‐Michael Peters

    Research Institute of Molecular Pathology, Austria

    11 publications · 3.3K citations

    11

    h-index

  2. GW
    Gordana Wutz

    Research Institute of Molecular Pathology, Austria

    5 publications · 1.7K citations

    5

    h-index

  3. KN
    Kim Nasmyth

    Research Institute of Molecular Pathology, Austria

    4 publications · 371 citations

    4

    h-index

  4. MB
    Maurici B. Roig

    University of Oxford, United Kingdom

    4 publications · 371 citations

    4

    h-index

  5. ED
    Elzo de Wit

    The Netherlands Cancer Institute, Netherlands

    4 publications · 330 citations

    4

    h-index

1–5 of 337

Institutions

123

  1. Research Institute of Molecular Pathology

    Vienna, Austria

    13 h-index

    86 publications

    31.1K citations

  2. Vienna Biocenter

    Vienna, Austria

    7 h-index

    53 publications

    17.6K citations

  3. Oncode Institute

    Utrecht, Netherlands

    5 h-index

    29 publications

    2.3K citations

  4. The Netherlands Cancer Institute

    Amsterdam, The Netherlands

    5 h-index

    38 publications

    3K citations

  5. University of Oxford

    Oxford, United Kingdom

    5 h-index

    20 publications

    2.3K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    10 publications

    1.2K citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    9 publications

    703 citations

  8. University of Vienna

    Vienna, Austria

    3 h-index

    4 publications

    937 citations

1–8 of 123

Venues

  1. eLife

    5 publications · 373 citations

    5

    h-index

  2. PLoS Genetics

    5 publications · 221 citations

    5

    h-index

  3. Nature

    4 publications · 1.2K citations

    4

    h-index

  4. Nature Structural & Molecular Biology

    3 publications · 286 citations

    3

    h-index

  5. Science

    3 publications · 805 citations

    3

    h-index

1–5