Concepedia

Volume-sensitive Signaling Pathways

Volume-Sensitive Signaling Pathways is a conceptual framework in cell physiology that denotes a class of intracellular signaling mechanisms specifically activated by changes in cellular volume, distinguishing them from other signaling pathways by their direct responsiveness to osmotic or mechanical perturbations that alter cell size.

70

Publications

3.5K

Citations

263

Authors

111

Institutions

Publications per year

2017–2026

5

Parents

Publications

70

Volume transmission in the brain. Novel mechanisms for neural transmission

Neuroscience Letters · 1992 · 386 citations

, , +16

Compressive Stress Inhibits Proliferation in Tumor Spheroids through a Volume Limitation

Morgan Delarue, Fabien Montel, Danijela Matic Vignjevic et al. · Biophysical Journal · 2014 · 298 citations

, , +16

Severe osmotic compression triggers a slowdown of intracellular signaling, which can be explained by molecular crowding

Agnès Miermont, François Waharte, Shiqiong Hu et al. · Proceedings of the National Academy of Sciences · 2013 · 231 citations

, , +17

WNK kinases sense molecular crowding and rescue cell volume via phase separation

Cary R. Boyd‐Shiwarski, Daniel J. Shiwarski, Shawn E. Griffiths et al. · Cell · 2022 · 195 citations · Full text

, , +13

Phosphatidylinositol 3-Kinase Contributes to Cell Volume Regulation through Effects on ATP Release

Andrew P. Feranchak, Richard M. Roman, Erik M. Schwiebert et al. · Journal of Biological Chemistry · 1998 · 112 citations · Full text

, , +14

1–5 of 70

Authors

263

  1. RM
    Richard M. Roman

    University of Colorado Health, United States

    3 publications · 270 citations

    3

    h-index

  2. FL
    Florian Läng

    University of Tübingen, Germany

    3 publications · 88 citations

    3

    h-index

  3. JF
    John Fitz

    University of Colorado Health, United States

    3 publications · 239 citations

    3

    h-index

  4. DS
    Dandan Sun

    University of Pittsburgh, United States

    3 publications · 257 citations

    3

    h-index

  5. AP
    Andrew P. Feranchak

    The University of Texas Southwestern Medical Center, United States

    3 publications · 239 citations

    3

    h-index

1–5 of 263

Institutions

111

  1. University of Pittsburgh

    Pittsburgh, United States

    4 h-index

    44 publications

    4.3K citations

  2. University of Copenhagen

    Copenhagen, Denmark

    4 h-index

    11 publications

    221 citations

  3. Mount Desert Island Biological Laboratory

    Bar Harbor, United States

    3 h-index

    5 publications

    206 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    8 publications

    1.2K citations

  5. University of Utah

    Salt Lake City, United States

    3 h-index

    10 publications

    773 citations

  6. University of Colorado Health

    Aurora, United States

    3 h-index

    10 publications

    547 citations

  7. Brigham and Women's Hospital

    Boston, United States

    2 h-index

    2 publications

    62 citations

  8. Laboratoire Matière et Systèmes Complexes

    Paris, France

    2 h-index

    4 publications

    991 citations

1–8 of 111

Venues

  1. Journal of Biological Chemistry

    JBC · 10 publications · 570 citations

    10

    h-index

  2. American Journal of Physiology-Cell Physiology

    7 publications · 327 citations

    7

    h-index

  3. PubMed

    Repository · 5 publications · 138 citations

    5

    h-index

  4. 5

    h-index

  5. 3

    h-index

1–5