Concepedia

Volume Of Distribution Optimization

Volume of Distribution Optimization is a pharmacokinetic modeling strategy that systematically refines the theoretical extent of drug dispersion in the body to enhance drug efficacy and safety by aligning the volume of distribution with desired physiological and therapeutic targets.

13

Publications

1.3K

Citations

58

Authors

22

Institutions

Publications per year

2017–2026

4

Parents

Publications

13

Mechanistic Approaches to Volume of Distribution Predictions: Understanding the Processes

Trudy Rodgers, Malcolm Rowland · Pharmaceutical Research · 2007 · 419 citations

, , +11

Volume of Distribution in Drug Design

Dennis A. Smith, Kevin Beaumont, Tristan S. Maurer et al. · Journal of Medicinal Chemistry · 2015 · 303 citations · Full text

, , +13

Intravitreal clearance and volume of distribution of compounds in rabbits: In silico prediction and pharmacokinetic simulations for drug development

Eva M. del Amo, Kati‐Sisko Vellonen, Heidi Kidron et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2015 · 146 citations

, , +17

Optimization of Drug Delivery

Richard J. Fleck · American Journal of Health-System Pharmacy · 1985 · 145 citations

, , +17

Exploring drug–protein interactions using the relationship between injection volume and capacity factor

Xinfeng Zhao, Qian Li, Jiejun Chen et al. · Journal of Chromatography A · 2014 · 43 citations

, , +16

1–5 of 13

Authors

58

  1. FL
    Franco Lombardo

    Pfizer (United States), United States

    1 publications · 41 citations

    1

    h-index

  2. ZL
    Zijian Li

    Peking University, China

    1 publications · 43 citations

    1

    h-index

  3. KV
    Kati‐Sisko Vellonen

    University of Eastern Finland, Finland

    1 publications · 146 citations

    1

    h-index

  4. FB
    Fabio Broccatelli

    University of Perugia, Italy

    1 publications · 42 citations

    1

    h-index

  5. HK
    Heidi Kidron

    University of Helsinki, Finland

    1 publications · 146 citations

    1

    h-index

1–5 of 58

Institutions

22

  1. Pfizer (United States)

    New York, United States

    1 h-index

    3 publications

    909 citations

  2. University of Illinois Chicago

    Chicago, United States

    1 h-index

    4 publications

    160 citations

  3. University Hospital Ulm

    Ulm, Germany

    1 h-index

    5 publications

    100 citations

  4. University of Chicago

    Chicago, United States

    1 h-index

    1 publications

    40 citations

  5. Walmart (United States)

    Bentonville, United States

    1 h-index

    1 publications

    303 citations

  6. Bethune International Peace Hospital

    Shijiazhuang, China

    1 h-index

    1 publications

    24 citations

  7. University of Manchester

    Manchester, United Kingdom

    1 h-index

    2 publications

    838 citations

  8. Liaoning University

    Shenyang, China

    1 h-index

    1 publications

    24 citations

1–8 of 22

Venues

  1. The American Journal of Emergency Medicine

    AJEM · 1 publications · 20 citations

    1

    h-index

  2. European Journal of Medicinal Chemistry

    1 publications · 24 citations

    1

    h-index

  3. IEEE Transactions on Biomedical Engineering

    1 publications · 40 citations

    1

    h-index

  4. American Journal of Health-System Pharmacy

    AJHP · 1 publications · 145 citations

    1

    h-index

  5. Pharmaceutical Research

    1 publications · 419 citations

    1

    h-index

1–5