Vesicle Tethering Complexes is a specialized multisubunit protein assembly that functions as a molecular bridge to mediate the initial recognition and physical tethering of transport vesicles to target membranes prior to SNARE-mediated membrane fusion, specifically regulating specificity in exocytic site organization and retrograde transport pathways.
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Stepwise assembly of functionally active transport vesicles
Joachim Ostermann, Lelio Orci, Katsuko Tani et al. · Cell · 1993 · 296 citations
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- PBPatrick Brennwald
University of North Carolina at Chapel Hill, United States
4 publications · 251 citations
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Yale University
New Haven, United States
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54 publications
6K citations
Princeton University
Princeton, United States
10 h-index
36 publications
3K citations
Howard Hughes Medical Institute
Chevy Chase, United States
10 h-index
25 publications
3.8K citations
Charles University
Prague, Czechia
9 h-index
33 publications
2.7K citations
Czech Academy of Sciences, Institute of Experimental Botany
Prague, Czechia
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46 publications
4.3K citations
MRC Laboratory of Molecular Biology
Cambridge, United Kingdom
6 h-index
11 publications
1.8K citations
University of Cambridge
Cambridge, United Kingdom
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Max Planck Society
Munich, Germany
5 h-index
8 publications
589 citations
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JBC · 12 publications · 703 citations
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PNAS · 6 publications · 397 citations
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