Concepedia

Variant-specific Antigen Expression

Variant-Specific Antigen Expression is a molecular mechanism in parasitic pathogens whereby a single variant surface glycoprotein is selectively transcribed and displayed on the host cell surface, enabling immune evasion through antigenic divergence from previously expressed variants.

62

Publications

3.3K

Citations

257

Authors

90

Institutions

Publications per year

2017–2026

3

Parents

Publications

62

The anatomy and transcription of a telomeric expression site for variant-specific surface antigens in T. brucei

Jan M. Kooter, Hans J. van der Spek, Ron Wagter et al. · Cell · 1987 · 217 citations

, , +10

Plasmodium falciparum Variant Surface Antigen Expression Patterns during Malaria

Peter C. Bull, Matthew Berriman, Sue Kyes et al. · PLoS Pathogens · 2005 · 195 citations · Full text

, , +14

RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes

L. H. T. Van der Ploeg, A. Y. C. Liu, Paul A.M. Michels et al. · Nucleic Acids Research · 1982 · 187 citations · Full text

, , +11

Splenic requirement for antigenic variation and expression of the variant antigen on the erythrocyte membrane in cloned Plasmodium knowlesi malaria

John W. Barnwell, R J Howard, H G Coon et al. · Infection and Immunity · 1983 · 154 citations · Full text

, , +16

Emergence of <i>Anaplasma marginale</i> Antigenic Variants during Persistent Rickettsemia

Dorothy French, Wendy C. Brown, Guy H. Palmer · Infection and Immunity · 1999 · 152 citations · Full text

, , +14

1–5 of 62

Authors

257

  1. MS
    M. Steinert

    Université Libre de Bruxelles, Belgium

    7 publications · 367 citations

    7

    h-index

  2. ÉP
    Étienne Pays

    Université Libre de Bruxelles, Belgium

    6 publications · 291 citations

    6

    h-index

  3. JW
    John W. Barnwell

    Centers for Disease Control and Prevention, United States

    5 publications · 266 citations

    5

    h-index

  4. LH
    Lars Hviid

    University of Copenhagen, Denmark

    4 publications · 269 citations

    4

    h-index

  5. RJ
    R J Howard

    National Institute of Allergy and Infectious Diseases, United States

    3 publications · 192 citations

    3

    h-index

1–5 of 257

Institutions

90

  1. Université Libre de Bruxelles

    Brussels, Belgium

    5 h-index

    16 publications

    756 citations

  2. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    5 h-index

    14 publications

    402 citations

  3. Wellcome Sanger Institute

    Cambridge, United Kingdom

    4 h-index

    8 publications

    679 citations

  4. National Institutes of Health

    Bethesda, United States

    4 h-index

    13 publications

    673 citations

  5. Copenhagen University Hospital

    Copenhagen, Denmark

    4 h-index

    14 publications

    1.3K citations

  6. Instituut voor Tropische Geneeskunde

    Antwerp, Belgium

    3 h-index

    8 publications

    344 citations

  7. University of Iowa

    Iowa City, United States

    3 h-index

    9 publications

    250 citations

  8. Rigshospitalet

    Copenhagen, Denmark

    3 h-index

    13 publications

    1.2K citations

1–8 of 90

Venues

  1. Infection and Immunity

    IAI · 10 publications · 691 citations

    10

    h-index

  2. Nucleic Acids Research

    6 publications · 416 citations

    6

    h-index

  3. Molecular and Cellular Biology

    MCB · 6 publications · 281 citations

    6

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 166 citations

    3

    h-index

  5. Journal of Biological Chemistry

    JBC · 3 publications · 67 citations

    3

    h-index

1–5