Concepedia

Vacuolar Acidification

Vacuolar Acidification is the process by which the vacuolar ATPase (V-ATPase) proton pump actively transports hydrogen ions into the vacuole, thereby establishing and maintaining an acidic internal pH essential for vacuolar function and cellular homeostasis.

332

Publications

26.2K

Citations

1.3K

Authors

425

Institutions

Publications per year

2017–2026

36

Parents

Publications

332

Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells.

Tamotsu Yoshimori, Akira Yamamoto, Yoshinori Moriyama et al. · Journal of Biological Chemistry · 1991 · 1.4K citations · Full text

, , +14

Lack of Acidification in <i>Mycobacterium</i> Phagosomes Produced by Exclusion of the Vesicular Proton-ATPase

Sheila Sturgill-Koszycki, Paul H. Schlesinger, Prasanta Chakraborty et al. · Science · 1994 · 1.3K citations

, , +16

Disassembly and Reassembly of the Yeast Vacuolar H+-ATPase in Vivo

Patricia M. Kane · Journal of Biological Chemistry · 1995 · 463 citations · Full text

, , +16

PH4 of Petunia Is an R2R3 MYB Protein That Activates Vacuolar Acidification through Interactions with Basic-Helix-Loop-Helix Transcription Factors of the Anthocyanin Pathway

Francesca Quattrocchio, Walter Verweij, Arthur R. Kroon et al. · The Plant Cell · 2006 · 420 citations · Full text

, , +15

Differential interaction with endocytic and exocytic pathways distinguish parasitophorous vacuoles of Coxiella burnetii and Chlamydia trachomatis

Robert A. Heinzen, Marci A. Scidmore, Daniel D. Rockey et al. · Infection and Immunity · 1996 · 399 citations · Full text

, , +16

1–5 of 332

Authors

1.3K

  1. PM
    Patricia M. Kane

    SUNY Upstate Medical University, United States

    14 publications · 1.6K citations

    14

    h-index

  2. TH
    Tom H. Stevens

    University of Oregon, United States

    12 publications · 881 citations

    12

    h-index

  3. DB
    Dennis Brown

    Massachusetts General Hospital, United States

    10 publications · 563 citations

    10

    h-index

  4. SL
    Stephen L. Gluck

    Washington University in St. Louis, United States

    9 publications · 2.1K citations

    9

    h-index

  5. YW
    Yoh Wada

    The University of Osaka, Japan

    8 publications · 504 citations

    8

    h-index

1–5 of 1.3K

Institutions

425

  1. Harvard University

    Cambridge, United States

    13 h-index

    41 publications

    2.5K citations

  2. Massachusetts General Hospital

    Boston, United States

    11 h-index

    43 publications

    2.6K citations

  3. University of Oregon

    Eugene, United States

    10 h-index

    35 publications

    2.9K citations

  4. University of Toronto

    Toronto, Canada

    9 h-index

    27 publications

    1.5K citations

  5. The University of Osaka

    Osaka, Japan

    9 h-index

    19 publications

    1.7K citations

  6. Hospital for Sick Children

    Toronto, Canada

    8 h-index

    32 publications

    3.6K citations

  7. Center for Systems Biology

    Boston, United States

    8 h-index

    22 publications

    1.1K citations

  8. Yale University

    New Haven, United States

    7 h-index

    15 publications

    1.2K citations

1–8 of 425

Venues

  1. Journal of Biological Chemistry

    JBC · 53 publications · 6.5K citations

    42

    h-index

  2. PLANT PHYSIOLOGY

    18 publications · 1.3K citations

    18

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 15 publications · 1.9K citations

    15

    h-index

  4. The Journal of Cell Biology

    JCB · 8 publications · 700 citations

    8

    h-index

  5. Journal of Cell Science

    7 publications · 574 citations

    7

    h-index

1–5