Concepedia

Urea-based Enhancers

Urea-Based Enhancers is a class of chemical permeation enhancers that utilize urea or its derivatives as the active agent to reversibly disrupt the stratum corneum's lipid matrix, thereby increasing the transdermal absorption of therapeutic molecules.

6

Publications

315

Citations

26

Authors

12

Institutions

Publications per year

2017–2026

0

Parents

Publications

6

Effect of Various Enhancers on Transdermal Penetration of Indomethacin and Urea, and Relationship between Penetration Parameters and Enhancement Factors

Taro OGISO, Masahiro Iwaki, Tsuyoshi Paku · Journal of Pharmaceutical Sciences · 1995 · 124 citations

, , +15

Urea analogues in propylene glycol as penetration enhancers in human skin

Adrian C. Williams, Brian Barry · International Journal of Pharmaceutics · 1989 · 57 citations

, , +17

The effect of urea and taurine as hydrophilic penetration enhancers on stratum corneum lipid models

Josefin Mueller, Joana Oliveira, Robert Barker et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2016 · 47 citations

, , +13

Unsaturated cyclic ureas as new non-toxic biodegradable transdermal penetration enhancers. II. Evaluation study

Ooi Wong, Noriko Tsuzuki, Ba Thu Nghiem et al. · International Journal of Pharmaceutics · 1989 · 36 citations

, , +14

Unsaturated Cyclic Ureas as New Nontoxic Biodegradable Transdermal Penetration Enhancers I: Synthesis

Ooi Wong, J. G. HUNTINGTON, Ryoji Konishi et al. · Journal of Pharmaceutical Sciences · 1988 · 29 citations

, , +9

1–5 of 6

Authors

26

  1. RK
    Ryoji Konishi

    Kagawa University, Japan

    2 publications · 65 citations

    2

    h-index

  2. JG
    J. G. HUNTINGTON

    Teikoku Seiyaku (Japan), Japan

    2 publications · 65 citations

    2

    h-index

  3. OW
    Ooi Wong

    University of Kansas, United States

    2 publications · 65 citations

    2

    h-index

  4. JH
    J. Howard Rytting

    University of Kansas, United States

    2 publications · 65 citations

    2

    h-index

  5. TH
    Tsunehiko Higuchi

    The University of Tokyo, Japan

    2 publications · 65 citations

    2

    h-index

1–5 of 26

Institutions

12

  1. Teikoku Seiyaku (Japan)

    Higashikagawa, Japan

    2 h-index

    4 publications

    137 citations

  2. Kindai University

    Osaka, Japan

    1 h-index

    3 publications

    372 citations

  3. University of New Mexico

    Albuquerque, United States

    1 h-index

    1 publications

    22 citations

  4. University of Kansas

    Lawrence, United States

    1 h-index

    4 publications

    116 citations

  5. National Institutes of Health

    Bethesda, United States

    1 h-index

    1 publications

    22 citations

  6. Martin Luther University Halle-Wittenberg

    Halle, Germany

    1 h-index

    3 publications

    141 citations

  7. Max Planck Institute of Colloids and Interfaces

    Potsdam, Germany

    1 h-index

    2 publications

    94 citations

  8. University of South Carolina

    Columbia, United States

    1 h-index

    2 publications

    44 citations

1–8 of 12

Venues

  1. International Journal of Pharmaceutics

    3 publications · 115 citations

    3

    h-index

  2. Journal of Pharmaceutical Sciences

    2 publications · 153 citations

    2

    h-index

  3. 1

    h-index

1–3