Concepedia

Universal Donor Cell Engineering

Universal Donor Cell Engineering is a genetic and cellular engineering framework designed to create immune-compatible donor cells by universally eliminating or modifying immunogenic determinants to prevent host immune rejection across diverse recipients.

12

Publications

1.9K

Citations

90

Authors

41

Institutions

Publications per year

2017–2026

1

Parents

Publications

12

Multiplex Genome Editing to Generate Universal CAR T Cells Resistant to PD1 Inhibition

Jiangtao Ren, Xiaojun Liu, Chongyun Fang et al. · Clinical Cancer Research · 2016 · 938 citations

, , +17

Toward eliminating HLA class I expression to generate universal cells from allogeneic donors

Hiroki Torikai, Andreas Reik, Frank Soldner et al. · Blood · 2013 · 305 citations

, , +16

Cellular senescence in human myoblasts is overcome by human telomerase reverse transcriptase and cyclin‐dependent kinase 4: consequences in aging muscle and therapeutic strategies for muscular dystrophies

Chun‐Hong Zhu, Vincent Mouly, R.N. Cooper et al. · Aging Cell · 2007 · 276 citations · Full text

, , +16

HLA Engineering of Human Pluripotent Stem Cells

Laura Riolobos, Roli K. Hirata, Cameron J. Turtle et al. · Molecular Therapy · 2013 · 251 citations · Full text

, , +17

Progress Toward Preparation of Universal Donor Red Cells

Glen L. Hortin, Hio-Tong Lok, Shu T. Huang · Artificial Cells Blood Substitutes and Biotechnology · 1997 · 32 citations · Full text

, , +14

1–5 of 12

Authors

90

  1. RC
    R.N. Cooper

    Sorbonne Université, France

    1 publications · 276 citations

    1

    h-index

  2. DA
    Danforth A. Newton

    Medical University of South Carolina, United States

    1 publications · 18 citations

    1

    h-index

  3. AB
    Anne Bigot

    Inserm, France

    1 publications · 276 citations

    1

    h-index

  4. GL
    Glen L. Hortin

    Washington University in St. Louis, United States

    1 publications · 32 citations

    1

    h-index

  5. JL
    Jack L. Strominger

    Harvard University, United States

    1 publications · 13 citations

    1

    h-index

1–5 of 90

Institutions

41

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    2 publications

    30 citations

  2. University of Pennsylvania

    Philadelphia, United States

    2 h-index

    8 publications

    5.7K citations

  3. Massachusetts Institute of Technology

    Cambridge, United States

    2 h-index

    3 publications

    337 citations

  4. Harvard University

    Cambridge, United States

    2 h-index

    4 publications

    80 citations

  5. Fred Hutch Cancer Center

    Seattle, United States

    2 h-index

    4 publications

    1.1K citations

  6. Inserm

    Paris, France

    2 h-index

    10 publications

    1.8K citations

  7. Institut de Chimie

    Paris, France

    1 h-index

    3 publications

    90 citations

  8. University of Washington

    Seattle, United States

    1 h-index

    8 publications

    2K citations

1–8 of 41

Venues

  1. Blood

    2 publications · 321 citations

    2

    h-index

  2. Molecular Therapy

    1 publications · 251 citations

    1

    h-index

  3. Nature Communications

    1 publications · 23 citations

    1

    h-index

  4. Eye

    1 publications · 14 citations

    1

    h-index

  5. The Journal of Immunology

    JI · 1 publications · 13 citations

    1

    h-index

1–5