Concepedia

Unfolding Kinetics

Unfolding Kinetics is a biophysical framework that characterizes the rate and pathway of protein structural disintegration under thermal stress, distinguishing it from equilibrium stability measures by focusing on the time-dependent dynamics of conformational loss in thermostability engineering.

2.4K

Publications

145.8K

Citations

6.6K

Authors

1.5K

Institutions

Publications per year

2017–2026

263

Parents

Publications

2.4K

Reversible Unfolding of Individual Titin Immunoglobulin Domains by AFM

Matthias Rief, Mathias Gautel, Filipp Oesterhelt et al. · Science · 1997 · 3.1K citations

, , +17

Denaturant <i>m</i> values and heat capacity changes: Relation to changes in accessible surface areas of protein unfolding

Jeffrey K. Myers, C. Nick Pace, J. Martin Scholtz · Protein Science · 1995 · 1.7K citations · Full text

, , +17

A thermodynamic approach to the problem of stabilization of globular protein structure: A calorimetric study

Peter L. Privalov · Journal of Molecular Biology · 1974 · 1.4K citations

, , +16

The stabilization of proteins by sucrose.

James Lee, Serge N. Timasheff · Journal of Biological Chemistry · 1981 · 1.1K citations · Full text

, , +17

Stability of proteins. Proteins which do not present a single cooperative system.

Peter L. Privalov · PubMed · 1982 · 1K citations

, , +10

1–5 of 2.4K

Authors

6.6K

  1. JB
    Jayant B. Udgaonkar

    National Centre for Biological Sciences, India

    27 publications · 986 citations

    21

    h-index

  2. PL
    Peter L. Privalov

    Johns Hopkins University, United States

    22 publications · 4.4K citations

    20

    h-index

  3. GI
    George I. Makhatadze

    Rensselaer Polytechnic Institute, United States

    20 publications · 1.9K citations

    20

    h-index

  4. PW
    Pernilla Wittung‐Stafshede

    Chalmers University of Technology, Sweden

    19 publications · 794 citations

    18

    h-index

  5. RL
    Robert L. Baldwin

    Stanford University, United States

    19 publications · 2.4K citations

    18

    h-index

1–5 of 6.6K

Institutions

1.5K

  1. National Institutes of Health

    Bethesda, United States

    31 h-index

    123 publications

    12.4K citations

  2. University of Pennsylvania

    Philadelphia, United States

    29 h-index

    116 publications

    12.9K citations

  3. Johns Hopkins University

    Baltimore, United States

    29 h-index

    86 publications

    9.8K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    29 h-index

    171 publications

    7.7K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    27 h-index

    68 publications

    9.1K citations

  6. Stanford University

    Stanford, United States

    27 h-index

    83 publications

    7.3K citations

  7. University of Cambridge

    Cambridge, United Kingdom

    27 h-index

    118 publications

    19.8K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    27 h-index

    82 publications

    9.3K citations

1–8 of 1.5K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 146 publications · 22.2K citations

    84

    h-index

  2. Biochemistry

    383 publications · 20.5K citations

    71

    h-index

  3. Journal of Molecular Biology

    JMB · 110 publications · 10.1K citations

    56

    h-index

  4. Journal of Biological Chemistry

    JBC · 126 publications · 10.4K citations

    56

    h-index

  5. Protein Science

    PS · 125 publications · 8.8K citations

    46

    h-index

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