Concepedia

Two-compartment Infusion Models

Two-Compartment Infusion Models is a pharmacokinetic model that describes the distribution and elimination of infused substances by dividing the body into a central compartment and a peripheral compartment, differing from single-compartment models through its representation of drug movement between these two kinetically distinct regions.

146

Publications

7.4K

Citations

809

Authors

294

Institutions

Publications per year

2017–2026

21

Parents

Publications

146

In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2.

Michael T. Lotze, Yvedt L. Matory, Stephen E. Ettinghausen et al. · The Journal of Immunology · 1985 · 614 citations

, , +9

Pharmacokinetics and Pharmacodynamics of Propofol Infusions during General Anesthesia

Audrey Shafer, Van A. Doze, Steven L. Shafer et al. · Anesthesiology · 1988 · 443 citations · Full text

, , +17

Experimental validation of measurements of glucose turnover in nonsteady state.

J. Radziuk, Kenneth H. Norwich, M. Vranić · American Journal of Physiology-Endocrinology and Metabolism · 1978 · 277 citations

, , +15

Clearance of Tissue Plasminogen Activator (TPA) and TPA/Plasminogen Activator Inhibitor Type 1 (PAI-1) Complex

Wayne L. Chandler, Marie‐Christine Alessi, M.F. Aillaud et al. · Circulation · 1997 · 245 citations

, , +16

Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport.

M W Schwartz, Richard N. Bergman, Steven E. Kahn et al. · Journal of Clinical Investigation · 1991 · 182 citations · Full text

, , +13

1–5 of 146

Authors

809

  1. SL
    Steven L. Shafer

    Stanford University, United States

    3 publications · 602 citations

    3

    h-index

  2. HS
    H. Schwilden

    Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany

    3 publications · 138 citations

    3

    h-index

  3. SG
    S. G. Rosen

    University of Michigan, United States

    3 publications · 122 citations

    3

    h-index

  4. WE
    William E. Evans

    St. Jude Children's Research Hospital, United States

    3 publications · 189 citations

    3

    h-index

  5. TB
    Thomas Bouillon

    University of Bonn, Germany

    3 publications · 158 citations

    3

    h-index

1–5 of 809

Institutions

294

  1. Cornell University

    Ithaca, United States

    4 h-index

    16 publications

    410 citations

  2. University of Michigan

    Ann Arbor, United States

    4 h-index

    15 publications

    705 citations

  3. St. Jude Children's Research Hospital

    Memphis, United States

    4 h-index

    4 publications

    288 citations

  4. University of Washington

    Seattle, United States

    4 h-index

    13 publications

    2.1K citations

  5. Lund University

    Lund, Sweden

    4 h-index

    9 publications

    622 citations

  6. Stanford University

    Stanford, United States

    3 h-index

    3 publications

    580 citations

  7. Marymount University

    Arlington, United States

    3 h-index

    5 publications

    308 citations

  8. University of California, Davis

    Davis, United States

    3 h-index

    9 publications

    240 citations

1–8 of 294

Venues

  1. Antimicrobial Agents and Chemotherapy

    AAC · 12 publications · 411 citations

    11

    h-index

  2. PubMed

    Repository · 9 publications · 402 citations

    9

    h-index

  3. Anesthesia & Analgesia

    8 publications · 478 citations

    8

    h-index

  4. Anesthesiology

    8 publications · 917 citations

    8

    h-index

  5. 6

    h-index

1–5