Concepedia

Transporter-mediated Barrier Dysfunction

Transporter-Mediated Barrier Dysfunction is a pathophysiological condition characterized by the disruption of blood-brain barrier integrity due to altered function or expression of solute carrier and ATP-binding cassette transporters, leading to aberrant neurovascular permeability and neurotoxic substance accumulation.

31

Publications

1.5K

Citations

200

Authors

89

Institutions

Publications per year

2017–2026

12

Parents

Publications

31

Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder

Dora C. Tărlungeanu, Elena Deliu, Christoph Dotter et al. · Cell · 2016 · 364 citations · Full text

, , +16

ABCG2 Is Upregulated in Alzheimer's Brain with Cerebral Amyloid Angiopathy and May Act as a Gatekeeper at the Blood–Brain Barrier for Aβ<sub>1–40</sub>Peptides

Huaqi Xiong, Debbie Callaghan, Aimee Jones et al. · Journal of Neuroscience · 2009 · 196 citations · Full text

, , +16

Impairment of brain endothelial glucose transporter by methamphetamine causes blood-brain barrier dysfunction

P. M. Abdul Muneer, Saleena Alikunju, Adam M. Szlachetka et al. · Molecular Neurodegeneration · 2011 · 104 citations · Full text

, , +15

Inhibition of Na + -K + -2Cl − cotransporter attenuates blood-brain-barrier disruption in a mouse model of traumatic brain injury

Jun Zhang, Hongjian Pu, Haiyue Zhang et al. · Neurochemistry International · 2017 · 68 citations

, , +15

Aging alters mRNA expression of amyloid transporter genes at the blood-brain barrier

Doreen Osgood, Miles C. Miller, Arthur A. Messier et al. · Neurobiology of Aging · 2017 · 63 citations · Full text

, , +16

1–5 of 31

Authors

200

  1. RN
    Rajesh N. Kalaria

    Case Western Reserve University, United States

    2 publications · 73 citations

    2

    h-index

  2. SI
    Sami I. Harik

    Case Western Reserve University, United States

    2 publications · 73 citations

    2

    h-index

  3. GD
    Gerald D. Silverberg

    Stanford University, United States

    2 publications · 79 citations

    2

    h-index

  4. AA
    Arthur A. Messier

    Brown University, United States

    2 publications · 79 citations

    2

    h-index

  5. LH
    Linda H. Bergersen

    University of Oslo, Norway

    2 publications · 80 citations

    2

    h-index

1–5 of 200

Institutions

89

  1. Brown University

    Providence, United States

    2 h-index

    9 publications

    332 citations

  2. University Hospitals of Cleveland

    Cleveland, United States

    2 h-index

    4 publications

    157 citations

  3. Yale University

    New Haven, United States

    2 h-index

    6 publications

    614 citations

  4. University of Oslo

    Oslo, Norway

    2 h-index

    6 publications

    220 citations

  5. Harvard University

    Cambridge, United States

    2 h-index

    2 publications

    34 citations

  6. RIKEN Center for Brain Science

    Wako, Japan

    1 h-index

    1 publications

    17 citations

  7. Institute of Science and Technology Austria

    Klosterneuburg, Austria

    1 h-index

    6 publications

    2.2K citations

  8. Instituto de Investigaciones Biomédicas Sols-Morreale

    Madrid, Spain

    1 h-index

    3 publications

    93 citations

1–8 of 89

Venues

  1. Neurobiology of Aging

    2 publications · 115 citations

    2

    h-index

  2. Advances in experimental medicine and biology

    Book series · 1 publications · 28 citations

    1

    h-index

  3. Journal of the Neurological Sciences

    1 publications · 40 citations

    1

    h-index

  4. Journal of Surgical Research

    JSR · 1 publications · 37 citations

    1

    h-index

  5. Pharmaceutical Research

    1 publications · 39 citations

    1

    h-index

1–5