Concepedia

Transcription-export Coupling

Transcription-Export Coupling is a molecular mechanism in eukaryotic gene expression that integrates the processes of mRNA transcription, processing, and nuclear export by physically and functionally linking the transcription machinery to the mRNA export apparatus, thereby ensuring the coordinated and efficient transit of mature, quality-controlled transcripts to the cytoplasm.

11

Publications

801

Citations

61

Authors

26

Institutions

Publications per year

2017–2026

2

Parents

Publications

11

Perinuclear Mlp proteins downregulate gene expression in response to a defect in mRNA export

Patrizia Vinciguerra, Nahid Iglesias, Jurgi Camblong et al. · The EMBO Journal · 2005 · 144 citations · Full text

, , +16

Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex

Andrew M. Ellisdon, Lyudmila Dimitrova-Paternoga, Ed Hurt et al. · Nature Structural & Molecular Biology · 2012 · 124 citations

, , +16

Interdependence between Transcription and mRNP Processing and Export, and Its Impact on Genetic Stability

Rosa Luna, Sonia Jimeno, Mercedes Marín et al. · Molecular Cell · 2005 · 115 citations · Full text

, , +14

Sem1 is a functional component of the nuclear pore complex–associated messenger RNA export machinery

Marius B. Faza, Stefan Kemmler, Sonia Jimeno et al. · The Journal of Cell Biology · 2009 · 107 citations · Full text

, , +16

Genome-wide mRNA surveillance is coupled to mRNA export

Haley Hieronymus, Michael Yu, Pamela A. Silver · Genes & Development · 2004 · 98 citations · Full text

, , +14

1–5 of 11

Authors

61

  1. EH
    Ed Hurt

    Heidelberg University, Germany

    3 publications · 254 citations

    3

    h-index

  2. MS
    Murray Stewart

    MRC Laboratory of Molecular Biology, United Kingdom

    2 publications · 147 citations

    2

    h-index

  3. AA
    Andrés Aguilera

    Universidad de Sevilla, Spain

    2 publications · 222 citations

    2

    h-index

  4. SJ
    Sonia Jimeno

    Universidad de Sevilla, Spain

    2 publications · 222 citations

    2

    h-index

  5. DJ
    Divyang Jani

    MRC Laboratory of Molecular Biology, United Kingdom

    1 publications · 23 citations

    1

    h-index

1–5 of 61

Institutions

26

  1. Heidelberg University

    Heidelberg, Germany

    3 h-index

    9 publications

    493 citations

  2. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    2 h-index

    4 publications

    294 citations

  3. Medical Research Council

    London, United Kingdom

    2 h-index

    4 publications

    294 citations

  4. Life Science Zurich

    Zurich, Switzerland

    1 h-index

    1 publications

    107 citations

  5. University of Regensburg

    Regensburg, Germany

    1 h-index

    2 publications

    30 citations

  6. UNSW Sydney

    Sydney, Australia

    1 h-index

    5 publications

    310 citations

  7. Centro Andaluz de Biología Molecular y Medicina Regenerativa

    Seville, Spain

    1 h-index

    3 publications

    321 citations

  8. Sutherland Hospital

    Caringbah, Australia

    1 h-index

    5 publications

    310 citations

1–8 of 26

Venues

  1. RNA

    1 publications · 69 citations

    1

    h-index

  2. Transcription

    1 publications · 19 citations

    1

    h-index

  3. The Journal of Cell Biology

    JCB · 1 publications · 107 citations

    1

    h-index

  4. Advanced Science

    1 publications · 62 citations

    1

    h-index

  5. Genes & Development

    1 publications · 98 citations

    1

    h-index

1–5