Transcription Pausing is a regulatory event in gene expression wherein RNA polymerase II temporarily halts transcriptional elongation downstream of initiation, distinct from transcription termination or promoter-proximal pausing, by stabilizing a paused elongation complex in response to specific cis-acting sequences and trans-acting factors.
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c-Myc Regulates Transcriptional Pause Release
Peter B. Rahl, Charles Y. Lin, Amy C. Seila et al. · Cell · 2010 · 1.3K citations · Full text
Structure of paused transcription complex Pol II–DSIF–NELF
Seychelle M. Vos, Lucas Farnung, Henning Urlaub et al. · Nature · 2018 · 396 citations
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University of Wisconsin–Madison
Madison, United States
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Ithaca, United States
20 h-index
60 publications
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Pennsylvania State University
State College, United States
18 h-index
78 publications
7.7K citations
Centre National de la Recherche Scientifique
Paris, France
13 h-index
84 publications
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Stanford University
Stanford, United States
11 h-index
30 publications
3K citations
University of Oxford
Oxford, United Kingdom
10 h-index
37 publications
3.1K citations
University of California, Berkeley
Berkeley, United States
10 h-index
23 publications
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National Institutes of Health
Bethesda, United States
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43 publications
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28 publications · 1.2K citations
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