Concepedia

Toxicity-driven Dose Reduction

Toxicity-Driven Dose Reduction is a clinical decision-making protocol that distinguishes itself from other dosing strategies by adjusting chemotherapeutic agents to lower levels in response to observed or anticipated treatment-related toxicities in individual patients.

37

Publications

1.3K

Citations

326

Authors

160

Institutions

Publications per year

2017–2026

16

Parents

Publications

37

Imatinib Disposition and ABCB1 (MDR1, P-Glycoprotein) Genotype

Howard Gurney, Ma‐Li Wong, Rosemary L. Balleine et al. · Clinical Pharmacology & Therapeutics · 2007 · 142 citations

, , +15

Low-Dose Monitored Mitotane Treatment Achieves the Therapeutic Range with Manageable Side Effects in Patients with Adrenocortical Cancer<sup>1</sup>

Massimo Terzolo, Anna Pia, Alfredo Berruti et al. · The Journal of Clinical Endocrinology & Metabolism · 2000 · 116 citations · Full text

, , +15

LungTech, an EORTC Phase II trial of stereotactic body radiotherapy for centrally located lung tumours: a clinical perspective

Sonja Adebahr, Sandra Collette, Emad Shash et al. · British Journal of Radiology · 2015 · 113 citations · Full text

, , +17

Safety, pharmacokinetics, and pharmacodynamic properties of oral DEBIO1143 (AT-406) in patients with advanced cancer: results of a first-in-man study

Herbert I. Hurwitz, David C. Smith, Henry C. Pitot et al. · Cancer Chemotherapy and Pharmacology · 2015 · 77 citations · Full text

, , +17

DPD-based adaptive dosing of 5-FU in patients with head and neck cancer: impact on treatment efficacy and toxicity

Chen Yang, Joseph Ciccolini, Aurore Blesius et al. · Cancer Chemotherapy and Pharmacology · 2010 · 77 citations

, , +16

1–5 of 37

Authors

326

  1. AG
    Antoine Giovanni

    Hôpital de la Timone, France

    2 publications · 87 citations

    2

    h-index

  2. DB
    D. Bagarry-Liégey

    Hôpital de la Timone, France

    2 publications · 87 citations

    2

    h-index

  3. JJ
    Jennifer J. Knox

    Princess Margaret Cancer Centre, Canada

    2 publications · 41 citations

    2

    h-index

  4. MZ
    M Zanaret

    Hôpital de la Timone, France

    2 publications · 87 citations

    2

    h-index

  5. JC
    Joseph Ciccolini

    Aix-Marseille Université, France

    2 publications · 87 citations

    2

    h-index

1–5 of 326

Institutions

160

  1. Westmead Institute

    Westmeadows, Australia

    2 h-index

    6 publications

    628 citations

  2. Princess Margaret Cancer Centre

    Toronto, Canada

    2 h-index

    6 publications

    123 citations

  3. Westmead Hospital

    Sydney, Australia

    2 h-index

    12 publications

    1.1K citations

  4. Novartis (United States)

    New York, United States

    2 h-index

    7 publications

    244 citations

  5. University of Michigan

    Ann Arbor, United States

    2 h-index

    3 publications

    174 citations

  6. University of Colorado Anschutz Medical Campus

    Aurora, United States

    1 h-index

    23 publications

    345 citations

  7. University Hospital of Zurich

    Zurich, Switzerland

    1 h-index

    1 publications

    113 citations

  8. The Honourable Society of Lincoln's Inn

    London, United Kingdom

    1 h-index

    1 publications

    18 citations

1–8 of 160

Venues

  1. Cancer Chemotherapy and Pharmacology

    5 publications · 214 citations

    5

    h-index

  2. Journal of Clinical Oncology

    2 publications · 31 citations

    2

    h-index

  3. JCO Oncology Practice

    2 publications · 38 citations

    2

    h-index

  4. Clinical Colorectal Cancer

    1 publications · 30 citations

    1

    h-index

  5. Journal of Internal Medicine

    1 publications · 17 citations

    1

    h-index

1–5