Concepedia

Topical Thrombin

Topical Thrombin is a hemostatic agent belonging to the class of enzymatic coagulants, distinguished by its direct application to bleeding surfaces to catalyze the conversion of fibrinogen to fibrin and thereby promote rapid localized blood clot formation in endodontic and oral surgical procedures.

108

Publications

5.3K

Citations

465

Authors

177

Institutions

Publications per year

2017–2026

8

Parents

Publications

108

Immunologic Impact and Clinical Outcomes After Surgical Exposure to Bovine Thrombin

Thomas L. Ortel, Meg C. Mercer, Elizabeth Thames et al. · Annals of Surgery · 2001 · 233 citations

, , +16

Development of antibodies to thrombin and factor V with recurrent bleeding in a patient exposed to topical bovine thrombin

LL Leung · Blood · 1990 · 190 citations · Full text

, , +14

Development of antibodies to thrombin and factor V with recurrent bleeding in a patient exposed to topical bovine thrombin

LL Leung · Blood · 1990 · 185 citations · Full text

, , +14

Fibrin glue in surgery: frequent development of inhibitors of bovine thrombin and human factor V

Hans Bänninger, Theres Hardegger, A Tobler et al. · British Journal of Haematology · 1993 · 177 citations

, , +16

A Phase 3, Randomized, Double-Blind Comparative Study of the Efficacy and Safety of Topical Recombinant Human Thrombin and Bovine Thrombin in Surgical Hemostasis

William C. Chapman, Neil Singla, Yuri Genyk et al. · Journal of the American College of Surgeons · 2007 · 173 citations

, , +14

1–5 of 108

Authors

465

  1. KG
    Kenneth G. Mann

    University of Vermont, United States

    4 publications · 265 citations

    4

    h-index

  2. WD
    William D. Spotnitz

    University of Virginia, United States

    4 publications · 147 citations

    4

    h-index

  3. WA
    W. Allan Alexander

    University of California, Davis, United States

    3 publications · 50 citations

    3

    h-index

  4. TL
    Thomas L. Ortel

    Duke Medical Center, United States

    3 publications · 297 citations

    3

    h-index

  5. DN
    David N. Fass

    Mayo Clinic, United States

    3 publications · 238 citations

    3

    h-index

1–5 of 465

Institutions

177

  1. University of Virginia Health System

    Charlottesville, United States

    5 h-index

    20 publications

    711 citations

  2. University of Southern California

    Los Angeles, United States

    4 h-index

    4 publications

    288 citations

  3. University of Minnesota

    Minneapolis, United States

    4 h-index

    17 publications

    914 citations

  4. Duke Medical Center

    Durham, United States

    4 h-index

    20 publications

    1.7K citations

  5. Allegheny General Hospital

    Pittsburgh, United States

    3 h-index

    5 publications

    406 citations

  6. Johnson & Johnson (United States)

    New Brunswick, United States

    3 h-index

    8 publications

    565 citations

  7. University of Manitoba

    Winnipeg, Canada

    3 h-index

    5 publications

    189 citations

  8. The University of Texas Medical Branch at Galveston

    Galveston, United States

    3 h-index

    11 publications

    1.1K citations

1–8 of 177

Venues

  1. PubMed

    Repository · 10 publications · 447 citations

    10

    h-index

  2. Journal of Biological Chemistry

    JBC · 5 publications · 334 citations

    5

    h-index

  3. The Laryngoscope

    4 publications · 195 citations

    4

    h-index

  4. 4

    h-index

  5. Thrombosis and Haemostasis

    3 publications · 175 citations

    3

    h-index

1–5