Concepedia

Top-down Sequencing

Top-Down Sequencing is a de novo peptide sequencing method that determines the complete amino acid sequence of an intact peptide directly from high-resolution tandem mass spectrometry data without prior enzymatic digestion or database lookup.

45

Publications

2K

Citations

205

Authors

78

Institutions

Publications per year

2017–2026

16

Parents

Publications

45

Top-down Protein Sequencing and MS3 on a Hybrid Linear Quadrupole Ion Trap-Orbitrap Mass Spectrometer

Boris Maček, Leonie F. Waanders, Jesper V. Olsen et al. · Molecular & Cellular Proteomics · 2006 · 198 citations · Full text

, , +16

Rational Selection of the Optimum MALDI Matrix for Top-Down Proteomics by In-Source Decay

Kevin Demeure, Loïc Quinton, Valérie Gabelica et al. · Analytical Chemistry · 2007 · 133 citations

, , +16

Congruent Strategies for Carbohydrate Sequencing. 3. OSCAR:  An Algorithm for Assigning Oligosaccharide Topology from MS<i><sup>n</sup></i> Data

Anthony J. Lapadula, Philip J. Hatcher, Andy Hanneman et al. · Analytical Chemistry · 2005 · 125 citations · Full text

, , +16

Native electrospray and electron-capture dissociation in FTICR mass spectrometry provide top-down sequencing of a protein component in an intact protein assembly

Hao Zhang, Weidong Cui, Jianzhong Wen et al. · Journal of the American Society for Mass Spectrometry · 2010 · 121 citations · Full text

, , +17

Top-down quantitation and characterization of SILAC-labeled proteins

Leonie F. Waanders, S. Hanke, Matthias Mann · Journal of the American Society for Mass Spectrometry · 2007 · 92 citations

, , +17

1–5 of 45

Authors

205

  1. ED
    Edwin De Pauw

    University of Liège, Belgium

    5 publications · 328 citations

    5

    h-index

  2. DS
    Detlev Suckau

    Bruker (Germany), Germany

    4 publications · 173 citations

    4

    h-index

  3. NT
    Nikola Tolić

    Pacific Northwest National Laboratory, United States

    3 publications · 102 citations

    3

    h-index

  4. XL
    Xiaowen Liu

    Indiana University – Purdue University Indianapolis, United States

    3 publications · 102 citations

    3

    h-index

  5. LQ
    Loïc Quinton

    University of Liège, Belgium

    3 publications · 265 citations

    3

    h-index

1–5 of 205

Institutions

78

  1. University of Liège

    Liège, Belgium

    5 h-index

    19 publications

    1.4K citations

  2. Bruker (Germany)

    Karlsruhe, Germany

    5 h-index

    21 publications

    1.2K citations

  3. Washington University in St. Louis

    St Louis, United States

    3 h-index

    13 publications

    1K citations

  4. Saint Petersburg Academic University

    Saint Petersburg, Russia

    3 h-index

    5 publications

    244 citations

  5. Erasmus MC

    Rotterdam, The Netherlands

    3 h-index

    9 publications

    306 citations

  6. Pacific Northwest National Laboratory

    Richland, United States

    3 h-index

    7 publications

    275 citations

  7. Environmental Molecular Sciences Laboratory

    Richland, United States

    3 h-index

    7 publications

    275 citations

  8. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    3 h-index

    4 publications

    173 citations

1–8 of 78

Venues

  1. Analytical Chemistry

    11 publications · 592 citations

    11

    h-index

  2. Journal of the American Society for Mass Spectrometry

    JASMS · 10 publications · 526 citations

    10

    h-index

  3. Journal of Proteome Research

    JPR · 2 publications · 162 citations

    2

    h-index

  4. Journal of Mass Spectrometry

    JMS · 2 publications · 63 citations

    2

    h-index

  5. International Journal of Mass Spectrometry

    2 publications · 32 citations

    2

    h-index

1–5