Concepedia

Time-resolved Single-molecule Dynamics

Time-Resolved Single-Molecule Dynamics is a methodological framework in single-molecule biophysics that enables the direct observation and quantification of conformational or positional changes of individual molecules over time with high temporal resolution, thereby distinguishing it from ensemble-averaged or static single-molecule measurements.

193

Publications

17.2K

Citations

804

Authors

268

Institutions

Publications per year

2017–2026

64

Parents

Publications

193

Zero-Mode Waveguides for Single-Molecule Analysis at High Concentrations

Michael J. Levene, Jonas Korlach, Stephen Turner et al. · Science · 2003 · 1.4K citations

, , +10

Real-time single-molecule observation of rolling-circle DNA replication

Nathan A. Tanner, Joseph J. Loparo, Samir M. Hamdan et al. · Nucleic Acids Research · 2009 · 1.3K citations · Full text

, , +11

High-density mapping of single-molecule trajectories with photoactivated localization microscopy

Suliana Manley, Jennifer M. Gillette, George H. Patterson et al. · Nature Methods · 2008 · 1.2K citations · Full text

, , +16

Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells

Jiji Chen, Zhengjian Zhang, Li Li et al. · Cell · 2014 · 648 citations · Full text

, , +16

Relaxation of a Single DNA Molecule Observed by Optical Microscopy

Thomas T. Perkins, Stephen R. Quake, Douglas E. Smith et al. · Science · 1994 · 634 citations

, , +16

1–5 of 193

Authors

804

  1. HP
    H. Peter Lu

    Bowling Green State University, United States

    6 publications · 139 citations

    6

    h-index

  2. HY
    Haw Yang

    Princeton University, United States

    5 publications · 363 citations

    5

    h-index

  3. SC
    Scott C. Blanchard

    Cornell University, United States

    5 publications · 711 citations

    5

    h-index

  4. BS
    Benjamin Schuler

    University of Zurich, Switzerland

    5 publications · 738 citations

    5

    h-index

  5. NV
    N.F. van Hulst

    University of Twente, Netherlands

    4 publications · 306 citations

    4

    h-index

1–5 of 804

Institutions

268

  1. Columbia University

    New York, United States

    9 h-index

    28 publications

    4.5K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    9 h-index

    37 publications

    3K citations

  3. Cornell University

    Ithaca, United States

    7 h-index

    19 publications

    5K citations

  4. Harvard University

    Cambridge, United States

    7 h-index

    17 publications

    2.2K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    7 h-index

    24 publications

    11.9K citations

  6. Stanford University

    Stanford, United States

    6 h-index

    24 publications

    4.3K citations

  7. The University of Tokyo

    Tokyo, Japan

    6 h-index

    26 publications

    1.4K citations

  8. Arizona State University

    Tempe, United States

    5 h-index

    22 publications

    552 citations

1–8 of 268

Venues

  1. Biophysical Journal

    12 publications · 1K citations

    12

    h-index

  2. The Journal of Physical Chemistry B

    9 publications · 362 citations

    9

    h-index

  3. The Journal of Chemical Physics

    9 publications · 448 citations

    9

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 863 citations

    7

    h-index

  5. Physical Review Letters

    PRL · 7 publications · 676 citations

    7

    h-index

1–5