Concepedia

Tim Barrels

TIM Barrels is a protein structural motif characterized by an (α/β)₈-barrel fold consisting of eight alternating alpha-helices and beta-strands that form a central barrel-like core, distinguished by its conserved three-dimensional architecture and frequent association with diverse enzymatic functions in metabolic pathways.

133

Publications

7.2K

Citations

623

Authors

256

Institutions

Publications per year

2017–2026

29

Variants

Alpha/beta BarrelAlpha/beta-barrelTim Barrel

Parents

Publications

133

A New UAG-Encoded Residue in the Structure of a Methanogen Methyltransferase

Bing Hao, Weimin Gong, Carey M. James et al. · Science · 2002 · 420 citations

, , +13

Natural history of S-adenosylmethionine-binding proteins

Piotr Koźbiał, Arcady Mushegian · BMC Structural Biology · 2005 · 294 citations · Full text

, , +14

De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy

Po‐Ssu Huang, Kaspar Feldmeier, Fabio Parmeggiani et al. · Nature Chemical Biology · 2015 · 268 citations · Full text

, , +14

High-Throughput Thermal Scanning: A General, Rapid Dye-Binding Thermal Shift Screen for Protein Engineering

Jason J. Lavinder, Sanjay B. Hari, Brandon J. Sullivan et al. · Journal of the American Chemical Society · 2009 · 220 citations · Full text

, , +15

Protein structure prediction by threading methods: Evaluation of current techniques

Christian M.‐R. Lemer, Marianne Rooman, Shoshana J. Wodak · Proteins Structure Function and Bioinformatics · 1995 · 209 citations

, , +16

1–5 of 133

Authors

623

  1. CR
    C. Robert Matthews

    Pennsylvania State University, United States

    19 publications · 705 citations

    17

    h-index

  2. RV
    Ramakrishna Vadrevu

    University of Massachusetts Chan Medical School, United States

    8 publications · 226 citations

    8

    h-index

  3. YW
    Ying Wu

    Huazhong University of Science and Technology, China

    7 publications · 285 citations

    7

    h-index

  4. BH
    Birte Höcker

    University of Bayreuth, Germany

    4 publications · 337 citations

    5

    h-index

  5. DB
    David Baker

    University of Washington, United States

    4 publications · 397 citations

    4

    h-index

1–5 of 623

Institutions

256

  1. University of Massachusetts Chan Medical School

    Worcester, United States

    17 h-index

    63 publications

    2.5K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    9 publications

    631 citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    14 publications

    334 citations

  4. University College London

    London, United Kingdom

    5 h-index

    18 publications

    1.5K citations

  5. University of Bayreuth

    Bayreuth, Germany

    4 h-index

    10 publications

    244 citations

  6. University of California San Diego

    San Diego, United States

    4 h-index

    5 publications

    319 citations

  7. Universidad Nacional Autónoma de México

    Mexico City, Mexico

    4 h-index

    15 publications

    677 citations

  8. University of Washington

    Seattle, United States

    4 h-index

    12 publications

    1.3K citations

1–8 of 256

Venues

  1. Journal of Molecular Biology

    JMB · 13 publications · 472 citations

    13

    h-index

  2. Proteins Structure Function and Bioinformatics

    11 publications · 716 citations

    11

    h-index

  3. Protein Science

    PS · 10 publications · 373 citations

    10

    h-index

  4. Journal of Biological Chemistry

    JBC · 7 publications · 451 citations

    7

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 6 publications · 428 citations

    6

    h-index

1–5