Concepedia

Thyroglobulin Processing

Thyroglobulin Processing is a biochemical mechanism in thyroid endocrinology whereby the precursor protein thyroglobulin undergoes post-translational modifications, intracellular trafficking, and lysosomal proteolysis to yield and release the active thyroid hormones thyroxine (T4) and triiodothyronine (T3) within thyroid follicular cells.

236

Publications

8.8K

Citations

730

Authors

253

Institutions

Publications per year

2017–2026

14

Parents

Publications

236

Primary structure of human thyroglobulin deduced from the sequence of its 8448-base complementary DNA

Yves Malthièry, Serge Lissitzky · European Journal of Biochemistry · 1987 · 325 citations

, , +15

Thyroid functions of mouse cathepsins B, K, and L

B. Friedrichs, Carmen Tepel, Thomas Reinheckel et al. · Journal of Clinical Investigation · 2003 · 223 citations · Full text

, , +17

Calnexin and BiP act as sequential molecular chaperones during thyroglobulin folding in the endoplasmic reticulum.

P.S. Kim, Peter Arvan · The Journal of Cell Biology · 1995 · 197 citations · Full text

, , +17

Glycoprotein synthesis in yeast. Identification of Man8GlcNAc2 as an essential intermediate in oligosaccharide processing.

James C. Byrd, Anthony L. Tarentino, Frank Maley et al. · Journal of Biological Chemistry · 1982 · 171 citations · Full text

, , +17

Up to date with human thyroglobulin

S.A. van de Graaf, Carrie Ris‐Stalpers, Erwin Pauws et al. · Journal of Endocrinology · 2001 · 150 citations · Full text

, , +15

1–5 of 236

Authors

730

  1. PA
    Peter Arvan

    University of Michigan, United States

    21 publications · 1.4K citations

    19

    h-index

  2. SL
    Serge Lissitzky

    Inserm, France

    14 publications · 744 citations

    13

    h-index

  3. HM
    Héctor M. Targovnik

    Universidad de Buenos Aires, Argentina

    10 publications · 492 citations

    10

    h-index

  4. GV
    Gilbert Vassart

    Université Libre de Bruxelles, Belgium

    10 publications · 513 citations

    10

    h-index

  5. BD
    Bruno Di Jeso

    University of Salento, Italy

    8 publications · 246 citations

    8

    h-index

1–5 of 730

Institutions

253

  1. Inserm

    Paris, France

    19 h-index

    111 publications

    3.3K citations

  2. Harvard University

    Cambridge, United States

    13 h-index

    31 publications

    1.9K citations

  3. University of Michigan

    Ann Arbor, United States

    11 h-index

    37 publications

    1.3K citations

  4. Universidad de Buenos Aires

    Buenos Aires, Argentina

    9 h-index

    28 publications

    1.4K citations

  5. University of Virginia

    Charlottesville, United States

    9 h-index

    26 publications

    1.2K citations

  6. Beth Israel Deaconess Hospital

    Plymouth, United States

    7 h-index

    19 publications

    1.4K citations

  7. Institut de Neurobiologie de la Méditerranée

    Marseille, France

    7 h-index

    36 publications

    863 citations

  8. Institute for Experimental Endocrinology and Oncology

    Naples, Italy

    7 h-index

    25 publications

    479 citations

1–8 of 253

Venues

  1. Journal of Biological Chemistry

    JBC · 25 publications · 1.4K citations

    22

    h-index

  2. Endocrinology

    39 publications · 995 citations

    20

    h-index

  3. Biochemical and Biophysical Research Communications

    BBRC · 15 publications · 351 citations

    13

    h-index

  4. The Journal of Clinical Endocrinology & Metabolism

    JCEM · 11 publications · 371 citations

    11

    h-index

  5. 8

    h-index

1–5