Concepedia

Thrombin-induced Platelet Aggregation

Thrombin-Induced Platelet Aggregation is a physiological assay that measures the extent and kinetics of platelet clumping in response to thrombin stimulation, distinguished by its specific activation of protease-activated receptors on platelets to initiate aggregation.

2.1K

Publications

118.4K

Citations

7.4K

Authors

1.6K

Institutions

Publications per year

2017–2026

145

Parents

Publications

2.1K

A dual thrombin receptor system for platelet activation

Mark L. Kahn, Yaowu Zheng, Weitong Huang et al. · Nature · 1998 · 975 citations

, , +14

Extracellular histones promote thrombin generation through platelet-dependent mechanisms: involvement of platelet TLR2 and TLR4

Fabrizio Semeraro, Concetta T. Ammollo, James H. Morrissey et al. · Blood · 2011 · 840 citations · Full text

, , +16

Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin

Mark L. Kahn, Mayumi Nakanishi‐Matsui, Michael J. Shapiro et al. · Journal of Clinical Investigation · 1999 · 833 citations · Full text

, , +16

Specific Synergy of Multiple Substrate–Receptor Interactions in Platelet Thrombus Formation under Flow

Brian Savage, Fanny Almus-Jacobs, Zaverio M. Ruggeri · Cell · 1998 · 806 citations · Full text

, , +16

The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways

Julia M. Burkhart, Marc Vaudel, Stepan Gambaryan et al. · Blood · 2012 · 774 citations · Full text

, , +15

1–5 of 2.1K

Authors

7.4K

  1. JF
    J. F. Mustard

    McMaster University, Canada

    38 publications · 2.4K citations

    26

    h-index

  2. HH
    Holm Holmsen

    University of Bergen, Norway

    30 publications · 1.3K citations

    19

    h-index

  3. CT
    Che‐Ming Teng

    National Taiwan University, Taiwan

    25 publications · 948 citations

    18

    h-index

  4. RL
    R L Kinlough-Rathbone

    McMaster University, Canada

    25 publications · 1.2K citations

    17

    h-index

  5. MP
    MA Packham

    McMaster University, Canada

    20 publications · 1.3K citations

    16

    h-index

1–5 of 7.4K

Institutions

1.6K

  1. Inserm

    Paris, France

    33 h-index

    362 publications

    15.8K citations

  2. Temple University

    Philadelphia, United States

    31 h-index

    173 publications

    11.2K citations

  3. McMaster University

    Hamilton, Canada

    26 h-index

    167 publications

    8.9K citations

  4. Harvard University

    Cambridge, United States

    25 h-index

    91 publications

    6.2K citations

  5. National Taiwan University

    Taipei, Taiwan

    24 h-index

    89 publications

    3.5K citations

  6. University of Toronto

    Toronto, Canada

    23 h-index

    147 publications

    8.6K citations

  7. Boston University

    Boston, United States

    21 h-index

    75 publications

    8.1K citations

  8. University of Pennsylvania

    Philadelphia, United States

    20 h-index

    84 publications

    8.6K citations

1–8 of 1.6K

Venues

  1. Journal of Biological Chemistry

    JBC · 115 publications · 13.9K citations

    72

    h-index

  2. Blood

    107 publications · 8.9K citations

    55

    h-index

  3. Thrombosis and Haemostasis

    231 publications · 8.5K citations

    51

    h-index

  4. Journal of Clinical Investigation

    JCI · 48 publications · 7.6K citations

    38

    h-index

  5. PubMed

    Repository · 128 publications · 4.1K citations

    34

    h-index

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