Concepedia

Threshold Responses In Patterning

Threshold Responses in Patterning is a developmental biology mechanism that determines discrete cell fate decisions along the anterior-posterior axis by activating distinct gene expression domains in response to specific concentration thresholds of morphogen gradients.

25

Publications

3K

Citations

79

Authors

46

Institutions

Publications per year

2017–2026

1

Parents

Publications

25

Direct and Long-Range Action of a DPP Morphogen Gradient

Denise Nellen, Richard Burke, Gary Struhl et al. · Cell · 1996 · 905 citations · Full text

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FINE-TUNED PHENOTYPES: TADPOLE PLASTICITY UNDER 16 COMBINATIONS OF PREDATORS AND COMPETITORS

Rick A. Relyea · Ecology · 2004 · 358 citations

, , +17

Binding affinities and cooperative interactions with bHLH activators delimit threshold responses to the dorsal gradient morphogen

Jie Jiang · Cell · 1993 · 328 citations · Full text

, , +16

Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix

Ainhoa Callejo, Carlos Torroja, Luis Quijada et al. · Development · 2006 · 141 citations

, , +16

Sharp developmental thresholds defined through bistability by antagonistic gradients of retinoic acid and FGF signaling

Albert Goldbeter, Didier Gonze, Olivier Pourquié · Developmental Dynamics · 2007 · 137 citations · Full text

, , +17

1–5 of 25

Authors

79

  1. AS
    Angelike Stathopoulos

    California Institute of Technology, United States

    2 publications · 169 citations

    2

    h-index

  2. NK
    Nikolai Kirov

    New York University, United States

    2 publications · 76 citations

    2

    h-index

  3. JC
    James C. Smith

    University of Cambridge, United Kingdom

    2 publications · 138 citations

    2

    h-index

  4. AE
    Albert Erives

    University of Iowa, United States

    2 publications · 68 citations

    2

    h-index

  5. CR
    Christine Rushlow

    New York University, United States

    2 publications · 76 citations

    2

    h-index

1–5 of 79

Institutions

46

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    3 publications

    1.1K citations

  2. New York University

    New York, United States

    3 h-index

    12 publications

    739 citations

  3. University of Pittsburgh

    Pittsburgh, United States

    2 h-index

    3 publications

    448 citations

  4. Wellcome Trust

    London, United Kingdom

    2 h-index

    3 publications

    236 citations

  5. The Gurdon Institute

    Cambridge, United Kingdom

    2 h-index

    3 publications

    236 citations

  6. California Institute of Technology

    Pasadena, United States

    2 h-index

    5 publications

    424 citations

  7. Hebrew University of Jerusalem

    Jerusalem, Israel

    1 h-index

    2 publications

    104 citations

  8. Karolinska Institutet

    Stockholm, Sweden

    1 h-index

    2 publications

    92 citations

1–8 of 46

Venues

  1. Development

    8 publications · 542 citations

    8

    h-index

  2. eLife

    2 publications · 127 citations

    2

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 182 citations

    2

    h-index

  4. Cell

    2 publications · 1.2K citations

    2

    h-index

  5. Ecology

    1 publications · 358 citations

    1

    h-index

1–5