Concepedia

Three-photon Microscopy

Three-Photon Microscopy is a nonlinear optical imaging technique that belongs to the class of multiphoton microscopy methods, distinguished by its reliance on the simultaneous absorption of three low-energy photons to excite a fluorophore, thereby enabling deeper tissue penetration and reduced out-of-focus background with improved spatial confinement compared to two-photon or single-photon approaches.

148

Publications

12.3K

Citations

737

Authors

290

Institutions

Publications per year

2017–2026

76

Variants

3Pm

Parents

Publications

148

Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation

Warren R. Zipfel, Rebecca M. Williams, Richard H. Christie et al. · Proceedings of the National Academy of Sciences · 2003 · 1.7K citations · Full text

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In vivo three-photon microscopy of subcortical structures within an intact mouse brain

Nicholas G. Horton, Ke Wang, Demirhan Kobat et al. · Nature Photonics · 2013 · 1.5K citations

, , +16

In vivo three-photon imaging of activity of GCaMP6-labeled neurons deep in intact mouse brain

Dimitre G. Ouzounov, Tianyu Wang, Mengran Wang et al. · Nature Methods · 2017 · 522 citations

, , +16

Measuring Serotonin Distribution in Live Cells with Three-Photon Excitation

Sudipta Maiti, Jason B. Shear, Rebecca M. Williams et al. · Science · 1997 · 418 citations

, , +17

Three-photon imaging of mouse brain structure and function through the intact skull

Tianyu Wang, Dimitre G. Ouzounov, Chunyan Wu et al. · Nature Methods · 2018 · 349 citations

, , +16

1–5 of 148

Authors

737

  1. CX
    Chris Xu

    Cornell University, United States

    21 publications · 3.8K citations

    19

    h-index

  2. KW
    Ke Wang

    Shenzhen University, China

    14 publications · 2.3K citations

    14

    h-index

  3. DG
    Dimitre G. Ouzounov

    Cornell University, United States

    11 publications · 1.4K citations

    11

    h-index

  4. TW
    Tianyu Wang

    Cornell University, United States

    9 publications · 1.3K citations

    9

    h-index

  5. XD
    Xiangquan Deng

    Shenzhen University, China

    8 publications · 323 citations

    8

    h-index

1–5 of 737

Institutions

290

  1. Cornell University

    Ithaca, United States

    22 h-index

    140 publications

    36.9K citations

  2. Shenzhen University

    Shenzhen, China

    13 h-index

    71 publications

    3.5K citations

  3. Zhejiang University

    Hangzhou, China

    8 h-index

    44 publications

    1.3K citations

  4. State Key Laboratory of Modern Optical Instruments

    Hangzhou, China

    8 h-index

    31 publications

    912 citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    7 h-index

    43 publications

    3.2K citations

  6. Massachusetts General Hospital

    Boston, United States

    5 h-index

    23 publications

    10.9K citations

  7. Harvard University

    Cambridge, United States

    5 h-index

    23 publications

    10.9K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    5 h-index

    29 publications

    1.7K citations

1–8 of 290

Venues

  1. Biomedical Optics Express

    BOE · 17 publications · 735 citations

    15

    h-index

  2. Optics Letters

    9 publications · 364 citations

    9

    h-index

  3. Nature Methods

    9 publications · 1.7K citations

    9

    h-index

  4. Bioimaging

    7 publications · 244 citations

    7

    h-index

  5. Optics Express

    5 publications · 183 citations

    5

    h-index

1–5