Concepedia

Therapy-induced Evolution

Therapy-Induced Evolution is a biological process in which cancer cells undergo selective pressures and adaptive changes in response to therapeutic interventions, leading to the emergence of resistant subclones and increased intratumoral heterogeneity.

52

Publications

6.5K

Citations

562

Authors

221

Institutions

Publications per year

2017–2026

31

Parents

Publications

52

Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma

Brett Johnson, Tali Mazor, Chibo Hong et al. · Science · 2013 · 1.4K citations

, , +17

Cancer therapy shapes the fitness landscape of clonal hematopoiesis

Kelly L. Bolton, Ryan Ptashkin, Teng Gao et al. · Nature Genetics · 2020 · 741 citations · Full text

, , +16

Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing

Ashley Maynard, Caroline E. McCoach, Julia Rotow et al. · Cell · 2020 · 699 citations · Full text

, , +17

Clonal evolution of chemotherapy-resistant urothelial carcinoma

Bishoy M. Faltas, Davide Prandi, Scott T. Tagawa et al. · Nature Genetics · 2016 · 301 citations · Full text

, , +14

Evolution of Resistance During Clonal Expansion

Yoh Iwasa, Martin A. Nowak, Franziska Michor · Genetics · 2006 · 249 citations · Full text

, , +16

1–5 of 52

Authors

562

  1. RA
    Robert A. Gatenby

    Moffitt Cancer Center, United States

    5 publications · 433 citations

    5

    h-index

  2. JS
    Joel S. Brown

    University of Illinois Chicago, United States

    3 publications · 195 citations

    3

    h-index

  3. JS
    Joel S. Brown

    Moffitt Cancer Center, United States

    3 publications · 324 citations

    3

    h-index

  4. MA
    Martin A. Nowak

    Harvard University, United States

    2 publications · 295 citations

    2

    h-index

  5. EH
    Elsa Hansen

    Center for Disease Dynamics, Economics & Policy, United States

    2 publications · 187 citations

    2

    h-index

1–5 of 562

Institutions

221

  1. Moffitt Cancer Center

    Tampa, United States

    9 h-index

    25 publications

    4.3K citations

  2. Harvard University

    Cambridge, United States

    5 h-index

    23 publications

    3.1K citations

  3. Johns Hopkins University

    Baltimore, United States

    3 h-index

    6 publications

    1.4K citations

  4. National Cancer Institute

    Bethesda, United States

    3 h-index

    5 publications

    2.4K citations

  5. The University of Texas MD Anderson Cancer Center

    Houston, United States

    3 h-index

    10 publications

    2.3K citations

  6. University of California, San Francisco

    San Francisco, United States

    3 h-index

    51 publications

    48.9K citations

  7. Dana-Farber Cancer Institute

    Boston, United States

    3 h-index

    5 publications

    2.3K citations

  8. Pennsylvania State University

    State College, United States

    3 h-index

    4 publications

    374 citations

1–8 of 221

Venues

  1. Cancer Research

    5 publications · 463 citations

    5

    h-index

  2. Nature Genetics

    3 publications · 1.1K citations

    3

    h-index

  3. Nature

    3 publications · 348 citations

    3

    h-index

  4. Nature Communications

    2 publications · 106 citations

    2

    h-index

  5. bioRxiv (Cold Spring Harbor Laboratory)

    Repository · 2 publications · 27 citations

    2

    h-index

1–5