Concepedia

Therapeutic Development

Therapeutic Development is a systematic research process within translational medicine that bridges basic scientific discoveries and clinical application by advancing potential interventions through preclinical and clinical stages to establish safety, efficacy, and practical therapeutic utility.

219

Publications

14.1K

Citations

547

Authors

326

Institutions

Publications per year

2017–2026

43

Parents

Children

Publications

219

Clinical development success rates for investigational drugs

Michael Hay, David W. Thomas, John L. Craighead et al. · Nature Biotechnology · 2014 · 2.5K citations

, , +12

The Economics of Reproducibility in Preclinical Research

Leonard P. Freedman, Iain Cockburn, Timothy Simcoe · PLoS Biology · 2015 · 1.1K citations · Full text

, , +11

Lost in translation: the valley of death across preclinical and clinical divide – identification of problems and overcoming obstacles

Attila A. Seyhan · Translational Medicine Communications · 2019 · 711 citations · Full text

, , +15

Reengineering Translational Science: The Time Is Right

Francis S. Collins · Science Translational Medicine · 2011 · 485 citations · Full text

, , +9

IDEAL framework for surgical innovation 1: the idea and development stages

Peter McCulloch, Jonathan Cook, Douglas G. Altman et al. · BMJ · 2013 · 354 citations · Full text

, , +5

1–5 of 219

Authors

547

  1. AO
    Adam O. Horvath

    Simon Fraser University, Canada

    4 publications · 433 citations

    4

    h-index

  2. LL
    Louis Lasagna

    Johns Hopkins University, United States

    4 publications · 253 citations

    4

    h-index

  3. AS
    Aaron S. Kesselheim

    Brigham and Women's Hospital, United States

    3 publications · 203 citations

    3

    h-index

  4. CP
    Christopher P. Austin

    National Institutes of Health, United States

    3 publications · 104 citations

    3

    h-index

  5. ER
    Eugénia Ribeiro

    University of Minho, Portugal

    3 publications · 208 citations

    3

    h-index

1–5 of 547

Institutions

326

  1. National Institutes of Health

    Bethesda, United States

    9 h-index

    13 publications

    473 citations

  2. Tufts University

    Medford, United States

    9 h-index

    15 publications

    937 citations

  3. Harvard University

    Cambridge, United States

    6 h-index

    13 publications

    713 citations

  4. Johns Hopkins University

    Baltimore, United States

    5 h-index

    5 publications

    116 citations

  5. Tufts Medical Center

    Boston, United States

    4 h-index

    4 publications

    306 citations

  6. National Center for Advancing Translational Sciences

    Rockville, United States

    4 h-index

    10 publications

    384 citations

  7. Simon Fraser University

    Burnaby, Canada

    4 h-index

    4 publications

    433 citations

  8. Vanderbilt University

    Nashville, United States

    4 h-index

    8 publications

    515 citations

1–8 of 326

Venues

  1. PubMed

    Repository · 12 publications · 262 citations

    10

    h-index

  2. Nature

    9 publications · 272 citations

    9

    h-index

  3. Clinical Pharmacology & Therapeutics

    CPT · 8 publications · 356 citations

    8

    h-index

  4. Psychotherapy

    6 publications · 287 citations

    6

    h-index

  5. Therapeutic Innovation & Regulatory Science

    TIRS · 5 publications · 95 citations

    6

    h-index

1–5