Concepedia

Testicular Complement System

The Testicular Complement System is a specialized immunological mechanism within the male reproductive system that comprises a locally regulated cascade of complement proteins which, under physiological conditions, maintains immune privilege in the testis by modulating inflammatory responses and preventing autoimmune attack against germ cells.

18

Publications

800

Citations

87

Authors

28

Institutions

Publications per year

2017–2026

2

Parents

Publications

18

Molecular cloning of a murine homologue of membrane cofactor protein (CD46): preferential expression in testicular germ cells

Akira Tsujimura, Kyoko Shida, Masaya Kitamura et al. · Biochemical Journal · 1998 · 166 citations · Full text

, , +13

Immunological and Testicular Response in Man Sensitized with Human Testicular Homogenate

Roberto E. Mancini, J.A. Andrada, D Saraceni et al. · The Journal of Clinical Endocrinology & Metabolism · 1965 · 110 citations

, , +17

Differential expression of complement regulatory proteins decay-accelerating factor (CD55), membrane cofactor protein (CD46) and CD59 during human spermatogenesis.

K L Simpson, C H Holmes · PubMed · 1994 · 62 citations · Full text

, , +15

Single-cell RNA sequencing reveals the fragility of male spermatogenic cells to Zika virus-induced complement activation

Wei Yang, Libo Liu, Feng‐Liang Liu et al. · Nature Communications · 2023 · 55 citations · Full text

, , +17

The incidence of sperm-associated immunoglobulin and C3, the third component of complement, in infertile men

Gilbert G. Haas, Alan D. Schreiber, Luis Blasco · Fertility and Sterility · 1983 · 54 citations

, , +13

1–5 of 18

Authors

87

  1. MM
    Masashi Mizuno

    Nagoya University, Japan

    2 publications · 40 citations

    2

    h-index

  2. GG
    Gilbert G. Haas

    University of Oklahoma Health Sciences Center, United States

    2 publications · 91 citations

    2

    h-index

  3. BP
    B. Paul Morgan

    Cardiff University, United Kingdom

    2 publications · 40 citations

    2

    h-index

  4. PW
    Peigang Wang

    Capital Medical University, China

    1 publications · 55 citations

    1

    h-index

  5. MD
    Matthias David

    Charité - Universitätsmedizin Berlin, Germany

    1 publications · 12 citations

    1

    h-index

1–5 of 87

Institutions

28

  1. Cardiff University

    Cardiff, United Kingdom

    2 h-index

    7 publications

    146 citations

  2. St Michael's Hospital

    Bristol, United Kingdom

    1 h-index

    1 publications

    62 citations

  3. Monash University

    Melbourne, Australia

    1 h-index

    1 publications

    40 citations

  4. St Michael’s Hospital

    London, United Kingdom

    1 h-index

    1 publications

    62 citations

  5. Eastern Virginia Medical School

    Norfolk, United States

    1 h-index

    2 publications

    54 citations

  6. Southern Illinois University Edwardsville

    Edwardsville, United States

    1 h-index

    1 publications

    40 citations

  7. University of Pennsylvania

    Philadelphia, United States

    1 h-index

    3 publications

    162 citations

  8. Texas Biomedical Research Institute

    San Antonio, United States

    1 h-index

    1 publications

    27 citations

1–8 of 28

Venues

  1. Science

    2 publications · 53 citations

    2

    h-index

  2. Reproduction

    2 publications · 81 citations

    2

    h-index

  3. Fertility and Sterility

    2 publications · 91 citations

    2

    h-index

  4. Biochemical Journal

    BJ · 2 publications · 199 citations

    2

    h-index

  5. PubMed

    Repository · 2 publications · 75 citations

    2

    h-index

1–5