Concepedia

Temporal Isoform Switching

Temporal Isoform Switching is a molecular phenomenon in which the relative abundance of alternative transcript isoforms from the same gene changes significantly across time, reflecting dynamic regulation of post-transcriptional processes during biological transitions.

19

Publications

17.3K

Citations

101

Authors

46

Institutions

Publications per year

2017–2026

4

Parents

Publications

19

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

Cole Trapnell, Brian A. Williams, Geo Pertea et al. · Nature Biotechnology · 2010 · 16.5K citations

, , +16

α6 Integrin Is Regulated with Lens Cell Differentiation by Linkage to the Cytoskeleton and Isoform Switching

Janice L. Walker, A. Sue Menko · Developmental Biology · 1999 · 96 citations

, , +16

Regional Differences in Troponin I Isoform Switching during Rat Heart Development

Luisa Gorza, Simonetta Ausoni, Nicoletta Merciai et al. · Developmental Biology · 1993 · 78 citations

, , +14

A myosin phosphatase targeting subunit isoform transition defines a smooth muscle developmental phenotypic switch

Wessel P. Dirksen, Franjo Vladic, Steven A. Fisher · American Journal of Physiology-Cell Physiology · 2000 · 73 citations

, , +17

Transitions from high to low molecular weight isoforms of CD45 (T200) involve rapid activation of alternate mRNA splicing and slow turnover of surface CD45R.

Julie P. Deans, A W Boyd, L M Pilarski · The Journal of Immunology · 1989 · 70 citations · Full text

, , +17

1–5 of 19

Authors

101

  1. WG
    Wenbin Guo

    James Hutton Institute, United Kingdom

    1 publications · 40 citations

    1

    h-index

  2. AM
    A M van Vlodrop

    Leiden University Medical Center, Netherlands

    1 publications · 39 citations

    1

    h-index

  3. MS
    Masao Sakaguchi

    Kyushu University, Japan

    1 publications · 13 citations

    1

    h-index

  4. PA
    Peter A. Cattini

    University of Manitoba, Canada

    1 publications · 52 citations

    1

    h-index

  5. AM
    Anne M. Murphy

    Johns Hopkins University, United States

    1 publications · 33 citations

    1

    h-index

1–5 of 101

Institutions

46

  1. Johns Hopkins University

    Baltimore, United States

    2 h-index

    7 publications

    180 citations

  2. Johns Hopkins Medicine

    Baltimore, United States

    2 h-index

    7 publications

    180 citations

  3. James Hutton Institute

    Dundee, United Kingdom

    1 h-index

    4 publications

    160 citations

  4. University of Maryland, College Park

    College Park, United States

    1 h-index

    3 publications

    49.5K citations

  5. Centre for Human Drug Research

    Leiden, The Netherlands

    1 h-index

    2 publications

    78 citations

  6. University of British Columbia

    Vancouver, Canada

    1 h-index

    4 publications

    196 citations

  7. Toyama Prefectural University

    Imizu, Japan

    1 h-index

    1 publications

    13 citations

  8. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    1 h-index

    3 publications

    210 citations

1–8 of 46

Venues

  1. Developmental Biology

    3 publications · 189 citations

    3

    h-index

  2. Journal of Biological Chemistry

    JBC · 2 publications · 96 citations

    2

    h-index

  3. BMC Genomics

    2 publications · 59 citations

    2

    h-index

  4. Journal of Molecular and Cellular Cardiology

    2 publications · 85 citations

    2

    h-index

  5. Plant Cell & Environment

    1 publications · 40 citations

    1

    h-index

1–5