Concepedia

Temperature-sensitive Lethal Mutations

Temperature-Sensitive Lethal Mutation is a type of conditional lethal mutation in which the mutant allele causes organismal death only under specific restrictive temperature conditions, while permitting survival and normal function at permissive temperatures.

455

Publications

30.6K

Citations

1.3K

Authors

327

Institutions

Publications per year

2017–2026

13

Variants

Temperature-sensitive Lethal Mutation

Parents

Publications

455

Two Pleiotropic Classes of daf-2 Mutation Affect Larval Arrest, Adult Behavior, Reproduction and Longevity in Caenorhabditis elegans

David Gems, Amy J Sutton, Mark Sundermeyer et al. · Genetics · 1998 · 731 citations · Full text

, , +17

Macromolecule Synthesis in Temperature-sensitive Mutants of Yeast

Leland H. Hartwell · Journal of Bacteriology · 1967 · 706 citations · Full text

, , +13

Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C.

Pamela B. Meluh, Douglas Koshland · Molecular Biology of the Cell · 1995 · 428 citations · Full text

, , +17

COLD-SENSITIVE CELL-DIVISION-CYCLE MUTANTS OF YEAST: ISOLATION, PROPERTIES, AND PSEUDOREVERSION STUDIES

Don Moir, Sue Stewart, Barbara C Osmond et al. · Genetics · 1982 · 371 citations

, , +17

Diverse effects of beta-tubulin mutations on microtubule formation and function.

Tim C. Huffaker, James H. Thomas, David Botstein · The Journal of Cell Biology · 1988 · 370 citations · Full text

, , +9

1–5 of 455

Authors

1.3K

  1. DT
    David T Suzuki

    University of British Columbia, Canada

    18 publications · 1.3K citations

    16

    h-index

  2. DB
    David Botstein

    Massachusetts Institute of Technology, United States

    7 publications · 1.4K citations

    7

    h-index

  3. TN
    Trisha N. Davis

    University of Washington, United States

    6 publications · 448 citations

    6

    h-index

  4. TA
    Thomas A. Grigliatti

    University of British Columbia, Canada

    6 publications · 690 citations

    6

    h-index

  5. BG
    Barry Ganetzky

    University of Wisconsin–Madison, United States

    5 publications · 611 citations

    5

    h-index

1–5 of 1.3K

Institutions

327

  1. University of British Columbia

    Vancouver, Canada

    17 h-index

    57 publications

    4.6K citations

  2. University of California, Irvine

    Irvine, United States

    12 h-index

    32 publications

    2.7K citations

  3. University of Wisconsin–Madison

    Madison, United States

    10 h-index

    23 publications

    1.6K citations

  4. California Institute of Technology

    Pasadena, United States

    10 h-index

    28 publications

    2.8K citations

  5. University of Washington

    Seattle, United States

    10 h-index

    32 publications

    2.8K citations

  6. Johns Hopkins University

    Baltimore, United States

    9 h-index

    28 publications

    2.4K citations

  7. Harvard University

    Cambridge, United States

    9 h-index

    25 publications

    2.3K citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    9 h-index

    33 publications

    3K citations

1–8 of 327

Venues

  1. Genetics

    75 publications · 5.7K citations

    41

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 37 publications · 3.8K citations

    30

    h-index

  3. Molecular and Cellular Biology

    MCB · 36 publications · 2.9K citations

    29

    h-index

  4. Journal of Bacteriology

    JB · 45 publications · 2.9K citations

    28

    h-index

  5. Developmental Biology

    21 publications · 1K citations

    17

    h-index

1–5