Concepedia

Telomere Position Effect

Telomere Position Effect is a gene regulatory phenomenon in which the proximity of a gene to a telomere results in its transcriptional silencing due to the spread of heterochromatin and associated repressive epigenetic modifications from the telomeric region into subtelomeric DNA.

84

Publications

8.4K

Citations

316

Authors

149

Institutions

Publications per year

2017–2026

4

Variants

Tpe

Parents

Publications

84

Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription

Daniel E. Gottschling, Oscar M. Aparicio, Barbara Billington et al. · Cell · 1990 · 1.3K citations

, , +17

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae

Oscar M. Aparicio, Barbara Billington, Daniel E. Gottschling · Cell · 1991 · 705 citations

, , +13

SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast.

Sabine Strahl‐Bolsinger, Andreas Hecht, Kang Luo et al. · Genes & Development · 1997 · 670 citations · Full text

, , +17

Position effect variegation in Drosophila is associated with an altered chromatin structure.

Lori L. Wallrath, Sarah C. R. Elgin · Genes & Development · 1995 · 476 citations · Full text

, , +15

Telomere Position Effect in Human Cells

Joseph A. Baur, Ying Zou, Jerry W. Shay et al. · Science · 2001 · 473 citations

, , +17

1–5 of 84

Authors

316

  1. VA
    Virginia A. Zakian

    Princeton University, United States

    9 publications · 1.9K citations

    9

    h-index

  2. DE
    Daniel E. Gottschling

    Fred Hutch Cancer Center, United States

    6 publications · 2.8K citations

    6

    h-index

  3. WE
    Woodring E. Wright

    The University of Texas Southwestern Medical Center, United States

    6 publications · 1.2K citations

    6

    h-index

  4. JM
    James M. Mason

    National Institute of Environmental Health Sciences, United States

    5 publications · 121 citations

    5

    h-index

  5. JW
    Jerry W. Shay

    The University of Texas Southwestern Medical Center, United States

    4 publications · 692 citations

    4

    h-index

1–5 of 316

Institutions

149

  1. The University of Texas Southwestern Medical Center

    Dallas, United States

    8 h-index

    28 publications

    5.3K citations

  2. Fred Hutch Cancer Center

    Seattle, United States

    7 h-index

    13 publications

    2.2K citations

  3. National Institute of Environmental Health Sciences

    Durham, United States

    5 h-index

    15 publications

    318 citations

  4. University of Chicago

    Chicago, United States

    5 h-index

    10 publications

    7K citations

  5. Princeton University

    Princeton, United States

    4 h-index

    8 publications

    354 citations

  6. Inserm

    Paris, France

    4 h-index

    11 publications

    676 citations

  7. Commissariat à l'Énergie Atomique et aux Énergies Alternatives

    Paris, France

    3 h-index

    5 publications

    421 citations

  8. University of California, Los Angeles

    Los Angeles, United States

    3 h-index

    10 publications

    3K citations

1–8 of 149

Venues

  1. Molecular and Cellular Biology

    MCB · 18 publications · 1K citations

    16

    h-index

  2. Genetics

    12 publications · 416 citations

    12

    h-index

  3. Genes & Development

    8 publications · 2.2K citations

    8

    h-index

  4. Nucleic Acids Research

    4 publications · 90 citations

    4

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 343 citations

    3

    h-index

1–5