Concepedia

Telomere Loop Formation

Telomere Loop Formation is a structural genomic mechanism in which the terminal segment of a telomere folds back and invades the double-stranded region to form a lariat-like structure, thereby shielding chromosome ends from DNA damage recognition and enabling telomere stability maintenance.

48

Publications

8.9K

Citations

213

Authors

91

Institutions

Publications per year

2017–2026

10

Variants

T-loop Formation

Parents

Publications

48

Mammalian Telomeres End in a Large Duplex Loop

Jack D. Griffith, Laurey Comeau, Soraya I. Rosenfield et al. · Cell · 1999 · 2.4K citations · Full text

, , +11

Telomeric DNA dimerizes by formation of guanine tetrads between hairpin loops

Wesley I. Sundquist, Aaron Klug · Nature · 1989 · 973 citations

, , +14

T‐loop assembly in vitro involves binding of TRF2 near the 3′ telomeric overhang

Rachel M. Stansel · The EMBO Journal · 2001 · 526 citations · Full text

, , +13

Homologous Recombination Generates T-Loop-Sized Deletions at Human Telomeres

Richard C. Wang, Agata Smogorzewska, Titia de Lange · Cell · 2004 · 507 citations

, , +10

Super-Resolution Fluorescence Imaging of Telomeres Reveals TRF2-Dependent T-loop Formation

Ylli Doksani, John Y. Wu, Titia de Lange et al. · Cell · 2013 · 491 citations · Full text

, , +14

1–5 of 48

Authors

213

  1. JD
    Jack D. Griffith

    University of North Carolina at Chapel Hill, United States

    9 publications · 3.1K citations

    9

    h-index

  2. TD
    Titia de Lange

    Rockefeller University, United States

    5 publications · 3.5K citations

    5

    h-index

  3. SW
    Smaranda Willcox

    University of North Carolina at Chapel Hill, United States

    4 publications · 233 citations

    4

    h-index

  4. AJ
    Anthony J. Cesare

    Children's Medical Research Institute, Australia

    4 publications · 637 citations

    4

    h-index

  5. RM
    Rachel M. Stansel

    University of North Carolina at Chapel Hill, United States

    3 publications · 3K citations

    3

    h-index

1–5 of 213

Institutions

91

  1. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    12 h-index

    31 publications

    12.8K citations

  2. Rockefeller University

    New York, United States

    8 h-index

    16 publications

    11.2K citations

  3. UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, United States

    4 h-index

    8 publications

    342 citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    2 h-index

    17 publications

    1.2K citations

  5. University of Copenhagen

    Copenhagen, Denmark

    2 h-index

    4 publications

    237 citations

  6. National Institute on Aging

    Baltimore, United States

    2 h-index

    13 publications

    1.7K citations

  7. Northwestern University

    Evanston, United States

    2 h-index

    11 publications

    1.1K citations

  8. Harvard University

    Cambridge, United States

    2 h-index

    12 publications

    1.9K citations

1–8 of 91

Venues

  1. Nucleic Acids Research

    6 publications · 264 citations

    6

    h-index

  2. The EMBO Journal

    5 publications · 1K citations

    5

    h-index

  3. Nature Communications

    4 publications · 324 citations

    4

    h-index

  4. Cell

    4 publications · 3.9K citations

    4

    h-index

  5. Molecular and Cellular Biology

    MCB · 2 publications · 397 citations

    2

    h-index

1–5