Concepedia

Target-site Evolution

Target-Site Evolution is a theoretical framework within the study of Target-Site Resistance that specifically accounts for the molecular and evolutionary mechanisms by which target proteins adapt to reduce binding affinity of inhibitory agents while maintaining biological function.

14

Publications

635

Citations

81

Authors

32

Institutions

Publications per year

2017–2026

5

Parents

Publications

14

HST Imaging of Atmospheric Phenomena Created by the Impact of Comet Shoemaker-Levy 9

Heidi B. Hammel, R. F. Beebe, Andrew P. Ingersoll et al. · Science · 1995 · 222 citations

, , +13

Impact of target site distribution for Type I restriction enzymes on the evolution of methicillin-resistant Staphylococcus aureus (MRSA) populations

Gareth A. Roberts, Patrick Houston, John H. White et al. · Nucleic Acids Research · 2013 · 71 citations · Full text

, , +17

Evolutionary dynamics of microRNA target sites across vertebrate evolution

Alfred Simkin, Alexa B. R. McIntyre, Andrew Grimson · PLoS Genetics · 2020 · 49 citations · Full text

, , +13

Analysis of yeast retrotransposon Ty insertions at the CAN1 locus.

Cailin Moira Wilke, Steven Heidler, Nicola J. Brown et al. · Genetics · 1989 · 43 citations · Full text

, , +16

Modeling HIV-1 Drug Resistance as Episodic Directional Selection

Ben Murrell, Túlio de Oliveira, Christopher J. Seebregts et al. · PLoS Computational Biology · 2012 · 43 citations · Full text

, , +12

1–5 of 14

Authors

81

  1. SW
    Shouhui Wei

    Chinese Academy of Agricultural Sciences, China

    2 publications · 52 citations

    2

    h-index

  2. ZH
    Zhaofeng Huang

    Chinese Academy of Agricultural Sciences, China

    2 publications · 52 citations

    2

    h-index

  3. CZ
    Chaoxian Zhang

    Chinese Academy of Agricultural Sciences, China

    2 publications · 52 citations

    2

    h-index

  4. HH
    Hongjuan Huang

    Chinese Academy of Agricultural Sciences, China

    2 publications · 52 citations

    2

    h-index

  5. TL
    Thérèsa L. Coetzer

    University of the Witwatersrand, South Africa

    1 publications · 14 citations

    1

    h-index

1–5 of 81

Institutions

32

  1. Institute of Plant Protection

    Beijing, China

    2 h-index

    13 publications

    352 citations

  2. Chinese Academy of Agricultural Sciences

    Beijing, China

    2 h-index

    13 publications

    352 citations

  3. Institut de Recherche pour le Développement

    Marseille, France

    1 h-index

    9 publications

    216 citations

  4. University of Hertfordshire

    Hatfield, United Kingdom

    1 h-index

    2 publications

    42 citations

  5. Instituto Paulo Gontijo

    São Paulo, Brazil

    1 h-index

    3 publications

    45 citations

  6. Anhui Science and Technology University

    Chuzhou, China

    1 h-index

    1 publications

    27 citations

  7. University of Arizona

    Tucson, United States

    1 h-index

    1 publications

    222 citations

  8. University of Michigan

    Ann Arbor, United States

    1 h-index

    1 publications

    222 citations

1–8 of 32

Venues

  1. Pesticide Biochemistry and Physiology

    PBP · 2 publications · 67 citations

    2

    h-index

  2. PLoS Genetics

    2 publications · 73 citations

    2

    h-index

  3. European Journal of Plant Pathology

    1 publications · 36 citations

    1

    h-index

  4. Genetics

    1 publications · 43 citations

    1

    h-index

  5. Journal of Molecular Evolution

    1 publications · 15 citations

    1

    h-index

1–5