Concepedia

Target-enzyme Mutation Analysis

Target-Enzyme Mutation Analysis is a molecular bioinformatics method that identifies and characterizes specific mutations in enzymes critical to amino acid biosynthesis pathways to assess their impact on inhibitor binding and catalytic function.

22

Publications

557

Citations

113

Authors

47

Institutions

Publications per year

2017–2026

4

Parents

Publications

22

Identification and characterization of a mutation in the dihydrofolate reductase gene from the methotrexate-resistant Chinese hamster ovary cell line Pro-3 MtxRIII.

Adam P. Dicker, Matthias Volkenandt, Barry Schweitzer et al. · Journal of Biological Chemistry · 1990 · 51 citations · Full text

, , +12

Structural and Mutational Analyses of the Interaction between the Barley α-Amylase/Subtilisin Inhibitor and the Subtilisin Savinase Reveal a Novel Mode of Inhibition

Pernille O. Micheelsen, J. Vévodová, Leonardo De Maria et al. · Journal of Molecular Biology · 2008 · 49 citations

, , +11

Mutational analysis of a feruloyl esterase from involved in substrate discrimination and pH dependence

TAKUYA KOSEKI, Kohei Takahashi, Shinya Fushinobu et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2005 · 46 citations

, , +16

Novel missense mutations in the human lysosomal sialidase gene in sialidosis patients and prediction of structural alterations of mutant enzymes

K Itoh, Yasunori Naganawa, Fumiko Matsuzawa et al. · Journal of Human Genetics · 2002 · 44 citations

, , +15

Expression and characterization of mutations in human very long-chain acyl-CoA dehydrogenase using a prokaryotic system

Eric S. Goetzman, Miao He, Al‐Walid Mohsen et al. · Molecular Genetics and Metabolism · 2007 · 43 citations · Full text

, , +13

1–5 of 22

Authors

113

  1. SK
    S. Kuramitsu

    The University of Osaka, Japan

    1 publications · 38 citations

    1

    h-index

  2. KI
    K Itoh

    Kurume University, Japan

    1 publications · 44 citations

    1

    h-index

  3. XZ
    Xiaoli Zhang

    Jilin University, China

    1 publications · 10 citations

    1

    h-index

  4. TY
    Takeshi Yamada

    Osaka City University, Japan

    1 publications · 44 citations

    1

    h-index

  5. PG
    Peter G. Schultz

    Scripps Research Institute, United States

    1 publications · 15 citations

    1

    h-index

1–5 of 113

Institutions

47

  1. Gifu University

    Gifu City, Japan

    1 h-index

    4 publications

    52 citations

  2. Indian Institute of Technology Roorkee

    Roorkee, India

    1 h-index

    7 publications

    196 citations

  3. Cornell University

    Ithaca, United States

    1 h-index

    5 publications

    255 citations

  4. Hamanomachi Hospital

    Fukuoka, Japan

    1 h-index

    1 publications

    44 citations

  5. Carlsberg Laboratory

    Copenhagen, Denmark

    1 h-index

    6 publications

    156 citations

  6. Kyushu University

    Fukuoka, Japan

    1 h-index

    3 publications

    132 citations

  7. Huazhong Agricultural University

    Wuhan, China

    1 h-index

    6 publications

    60 citations

  8. Memorial Sloan Kettering Cancer Center

    New York, United States

    1 h-index

    5 publications

    255 citations

1–8 of 47

Venues

  1. Biochemical and Biophysical Research Communications

    BBRC · 3 publications · 75 citations

    3

    h-index

  2. Journal of Biological Chemistry

    JBC · 2 publications · 77 citations

    2

    h-index

  3. BMC Bioinformatics

    1 publications · 22 citations

    1

    h-index

  4. Journal of Molecular Catalysis B Enzymatic

    1 publications · 10 citations

    1

    h-index

  5. Journal of Medicinal Chemistry

    1 publications · 14 citations

    1

    h-index

1–5