Concepedia

Systemic Exposure Changes

Systemic Exposure Changes is a pharmacokinetic phenomenon characterized by alterations in the concentration-time profile of a drug in the systemic circulation resulting from the concomitant administration of another drug, thereby affecting its absorption, distribution, metabolism, or excretion.

94

Publications

3.6K

Citations

645

Authors

246

Institutions

Publications per year

2017–2026

25

Parents

Publications

94

Levels of metal ions after small- and large-diameter metal-on-metal hip arthroplasty

M. Clarke, P. T. H. Lee, Aman Arora et al. · Journal of Bone and Joint Surgery - British Volume · 2003 · 245 citations

, , +16

Phase I Clinical Trial of Recombinant Human Endostatin Administered as a Short Intravenous Infusion Repeated Daily

Joseph P. Eder, Jeffrey G. Supko, Jeffrey W. Clark et al. · Journal of Clinical Oncology · 2002 · 245 citations

, , +16

Safety of Converting From Tetrabenazine to Deutetrabenazine for the Treatment of Chorea

Samuel Frank, David Stamler, Elise Kayson et al. · JAMA Neurology · 2017 · 212 citations

, , +14

The relationship between ritonavir plasma levels and side-effects: implications for therapeutic drug monitoring

Giorgio Gatti, Antonio Di Biagio, R Casazza et al. · AIDS · 1999 · 177 citations

, , +16

Improved regional selectivity of hepatic arterial bcnu with degradable microspheres

Shaker R. Dakhil, William D. Ensminger, Kyung Cho et al. · Cancer · 1982 · 144 citations

, , +15

1–5 of 94

Authors

645

  1. DC
    David C. Hohn

    The University of Texas MD Anderson Cancer Center, United States

    3 publications · 53 citations

    3

    h-index

  2. AÅ
    Anders Åsberg

    University of Oslo, Norway

    3 publications · 146 citations

    3

    h-index

  3. IB
    I B Skottheim

    University of Oslo, Norway

    2 publications · 126 citations

    2

    h-index

  4. RS
    Rune Sandbu

    Sykehuset i Vestfold, Norway

    2 publications · 126 citations

    2

    h-index

  5. TO
    Tadao Okamoto

    Kyushu University, Japan

    2 publications · 36 citations

    2

    h-index

1–5 of 645

Institutions

246

  1. St. Jude Children's Research Hospital

    Memphis, United States

    3 h-index

    11 publications

    223 citations

  2. University of Oslo

    Oslo, Norway

    3 h-index

    12 publications

    649 citations

  3. The University of Texas MD Anderson Cancer Center

    Houston, United States

    3 h-index

    18 publications

    375 citations

  4. Bristol-Myers Squibb (United States)

    New York, United States

    2 h-index

    7 publications

    167 citations

  5. Jilin University

    Changchun, China

    2 h-index

    18 publications

    329 citations

  6. University of Genoa

    Genoa, Italy

    2 h-index

    10 publications

    1.2K citations

  7. Chinese University of Hong Kong

    Hong Kong, Hong Kong

    2 h-index

    12 publications

    642 citations

  8. Marymount University

    Arlington, United States

    2 h-index

    5 publications

    574 citations

1–8 of 246

Venues

  1. PubMed

    Repository · 6 publications · 156 citations

    6

    h-index

  2. British Journal of Clinical Pharmacology

    BJCP · 5 publications · 133 citations

    5

    h-index

  3. Drug Metabolism and Disposition

    4 publications · 113 citations

    4

    h-index

  4. Clinical Pharmacology & Therapeutics

    CPT · 3 publications · 139 citations

    3

    h-index

  5. Biopharmaceutics & Drug Disposition

    3 publications · 116 citations

    3

    h-index

1–5