Concepedia

Synthetic Impurity Profiling

Synthetic Impurity Profiling is a systematic analytical methodology within impurity fate studies that identifies, characterizes, and quantifies structurally defined impurities arising from chemical synthesis pathways, distinguished by its focus on the origin, transformation, and persistence of synthetic by-products in pharmaceutical or chemical manufacturing processes.

23

Publications

616

Citations

136

Authors

52

Institutions

Publications per year

2017–2026

6

Parents

Publications

23

Detection and quantitation of synthetic cannabinoid receptor agonists in infused papers from prisons in a constantly evolving illicit market

Caitlyn Norman, Gillian Walker, Brian McKirdy et al. · Drug Testing and Analysis · 2020 · 96 citations · Full text

, , +14

Impurity Profiling to Match a Nerve Agent to Its Precursor Source for Chemical Forensics Applications

Carlos G. Fraga, Gabriel A. Pérez Acosta, Michael D. Crenshaw et al. · Analytical Chemistry · 2011 · 61 citations

, , +14

Potential impurities in drug substances: Compound-specific toxicology limits for 20 synthetic reagents and by-products, and a class-specific toxicology limit for alkyl bromides

Joel P. Bercu, Sheila M. Galloway, Patricia Parris et al. · Regulatory Toxicology and Pharmacology · 2018 · 47 citations

, , +14

Impurity profiling of methylamphetamine in Australia and the development of a national drugs database

M.B. Perkal, Y.L. Ng, James R. Pearson · Forensic Science International · 1994 · 46 citations

, , +14

Determination of synthesis route of 1-(3,4-methylenedioxyphenyl)-2-propanone (MDP-2-P) based on impurity profiles of MDMA

M. Świst, Jarosław Wilamowski, Dariusz Zuba et al. · Forensic Science International · 2004 · 32 citations · Full text

, , +9

1–5 of 23

Authors

136

  1. JH
    Jos Hoogmartens

    KU Leuven, Belgium

    2 publications · 34 citations

    2

    h-index

  2. UH
    Ulrike Holzgrabe

    University of Würzburg, Germany

    2 publications · 41 citations

    2

    h-index

  3. AV
    Ann Van Schepdael

    KU Leuven, Belgium

    2 publications · 34 citations

    2

    h-index

  4. EA
    Erwin Adams

    KU Leuven, Belgium

    2 publications · 34 citations

    2

    h-index

  5. JR
    James R. Pearson

    Victoria Police, Australia

    2 publications · 71 citations

    2

    h-index

1–5 of 136

Institutions

52

  1. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    7 publications

    140 citations

  2. Boehringer Ingelheim (United States)

    Ridgefield, United States

    2 h-index

    2 publications

    58 citations

  3. Novartis (Switzerland)

    Basel, Switzerland

    2 h-index

    13 publications

    167 citations

  4. KU Leuven

    Leuven, Belgium

    2 h-index

    7 publications

    117 citations

  5. Eli Lilly (United States)

    Indianapolis, United States

    2 h-index

    9 publications

    127 citations

  6. Victoria Police

    Docklands, Australia

    2 h-index

    4 publications

    163 citations

  7. AbbVie (United States)

    North Chicago, United States

    2 h-index

    2 publications

    58 citations

  8. University of Würzburg

    Würzburg, Germany

    2 h-index

    4 publications

    82 citations

1–8 of 52

Venues

  1. Forensic Science International

    5 publications · 137 citations

    5

    h-index

  2. 4

    h-index

  3. Organic Process Research & Development

    4 publications · 57 citations

    4

    h-index

  4. Analytical Chemistry

    3 publications · 88 citations

    3

    h-index

  5. Journal of Chromatography A

    1 publications · 24 citations

    1

    h-index

1–5