Synonymous Selection is a molecular evolutionary phenomenon in which natural selection acts on synonymous mutations—nucleotide changes that do not alter the encoded amino acid—thereby influencing the fitness of an organism through mechanisms such as mRNA stability, translation efficiency, or co-translational protein folding.
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15
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A high-resolution map of human evolutionary constraint using 29 mammals
Kerstin Lindblad‐Toh, Manuel Garber, Or Zuk et al. · Nature · 2011 · 1.2K citations · Full text
Strong Purifying Selection at Synonymous Sites in D. melanogaster
David S. Lawrie, Philipp W. Messer, Ruth Hershberg et al. · PLoS Genetics · 2013 · 262 citations · Full text
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Universitat de Barcelona
Barcelona, Spain
4 h-index
5 publications
374 citations
University of Edinburgh
Edinburgh, United Kingdom
4 h-index
13 publications
911 citations
University of Bath
Bath, United Kingdom
4 h-index
8 publications
1.2K citations
Beijing Normal University
Beijing, China
4 h-index
7 publications
313 citations
University of Iowa
Iowa City, United States
3 h-index
3 publications
298 citations
Rutgers, The State University of New Jersey
New Brunswick, United States
3 h-index
4 publications
794 citations
Cornell University
Ithaca, United States
3 h-index
6 publications
3.7K citations
University of Chicago
Chicago, United States
3 h-index
5 publications
920 citations
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- Molecular Biology and Evolution
MBE · 13 publications · 1.1K citations
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PNAS · 8 publications · 1.2K citations
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- Genetics
6 publications · 764 citations
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- BMC Evolutionary Biology
4 publications · 179 citations
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- PLoS ONE
2 publications · 127 citations
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