Concepedia

Synaptotagmin-mediated Release

Synaptotagmin-Mediated Release is a molecular mechanism of calcium-regulated synaptic vesicle exocytosis in which the calcium sensor synaptotagmin triggers membrane fusion by interacting with SNARE complexes and phospholipids to ensure rapid and synchronous neurotransmitter release.

519

Publications

54.1K

Citations

1.8K

Authors

502

Institutions

Publications per year

2017–2026

97

Parents

Publications

519

Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins

Gero Miesenböck, Dino A. De Angelis, James E. Rothman · Nature · 1998 · 2.6K citations

, , +14

Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse

Martin Geppert, Yukiko Goda, Robert E. Hammer et al. · Cell · 1994 · 1.5K citations · Full text

, , +16

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

Mark K. Bennett, Nicole Calakos, Richard H. Scheller · Science · 1992 · 1.3K citations

, , +17

STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis

Katrin I. Willig, Silvio O. Rizzoli, Volker Westphal et al. · Nature · 2006 · 1.2K citations

, , +13

Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface

Nils Brose, Alexander G. Petrenko, Thomas C. Südhof et al. · Science · 1992 · 991 citations

, , +17

1–5 of 519

Authors

1.8K

  1. TC
    Thomas C. Südhof

    Howard Hughes Medical Institute, United States

    53 publications · 11.9K citations

    48

    h-index

  2. ER
    Edwin R. Chapman

    University of Wisconsin–Madison, United States

    46 publications · 4.8K citations

    35

    h-index

  3. MF
    Mitsunori Fukuda

    Tohoku University, Japan

    38 publications · 2.8K citations

    30

    h-index

  4. JR
    Josep Rizo

    The University of Texas Southwestern Medical Center, United States

    30 publications · 4.7K citations

    28

    h-index

  5. KM
    Katsuhiko Mikoshiba

    RIKEN Center for Brain Science, Japan

    21 publications · 1.7K citations

    21

    h-index

1–5 of 1.8K

Institutions

502

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    72 h-index

    376 publications

    71.5K citations

  2. The University of Texas Southwestern Medical Center

    Dallas, United States

    46 h-index

    220 publications

    48K citations

  3. University of Wisconsin–Madison

    Madison, United States

    36 h-index

    168 publications

    19.5K citations

  4. Stanford University

    Stanford, United States

    30 h-index

    136 publications

    22.4K citations

  5. Max Planck Institute for Biophysical Chemistry

    Göttingen, Germany

    28 h-index

    92 publications

    19.6K citations

  6. Yale University

    New Haven, United States

    25 h-index

    115 publications

    14.7K citations

  7. The University of Tokyo

    Tokyo, Japan

    20 h-index

    36 publications

    2.2K citations

  8. RIKEN Center for Brain Science

    Wako, Japan

    17 h-index

    44 publications

    3.1K citations

1–8 of 502

Venues

  1. Journal of Biological Chemistry

    JBC · 52 publications · 5.1K citations

    42

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 42 publications · 4.4K citations

    37

    h-index

  3. Journal of Neuroscience

    37 publications · 3K citations

    29

    h-index

  4. Neuron

    25 publications · 4.7K citations

    24

    h-index

  5. eLife

    24 publications · 1.5K citations

    18

    h-index

1–5