Concepedia

Synaptic Network Hyperexcitability

Synaptic Network Hyperexcitability is a neurobiological construct characterized by an abnormal elevation in the collective responsiveness of synaptic networks to neuronal inputs, distinguished from baseline excitability by its sustained, pathologically amplified signaling dynamics that predispose neural circuits to dysfunctional firing patterns.

70

Publications

5.1K

Citations

403

Authors

164

Institutions

Publications per year

2017–2026

25

Parents

Publications

70

Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models

Michelle Antoine, Tomer Langberg, Philipp Schnepel et al. · Neuron · 2019 · 426 citations · Full text

, , +16

Excitatory/Inhibitory Synaptic Imbalance Leads to Hippocampal Hyperexcitability in Mouse Models of Tuberous Sclerosis

Helen S. Bateup, Caroline A. Johnson, Cassandra Denefrio et al. · Neuron · 2013 · 347 citations

, , +17

Neuronal hyperactivity – A key defect in Alzheimer's disease?

Marc Aurel Busche, Arthur Konnerth · BioEssays · 2015 · 275 citations

, , +17

Environment Matters: Synaptic Properties of Neurons Born in the Epileptic Adult Brain Develop to Reduce Excitability

Katherine Jakubs, Avtandil Nanobashvili, Sara Bonde et al. · Neuron · 2006 · 252 citations · Full text

, , +17

Some properties of unresponsive cells in the cerebral cortex

K. Krnjević, Susan M. Schwartz · Experimental Brain Research · 1967 · 211 citations

, , +12

1–5 of 70

Authors

403

  1. FB
    Fabio Benfenati

    Italian Institute of Technology, Italy

    4 publications · 289 citations

    4

    h-index

  2. AF
    Anna Fassio

    University of Genoa, Italy

    3 publications · 176 citations

    3

    h-index

  3. PB
    Pietro Baldelli

    University of Genoa, Italy

    3 publications · 265 citations

    3

    h-index

  4. JL
    Jeffrey L. Noebels

    Baylor College of Medicine, United States

    3 publications · 95 citations

    3

    h-index

  5. FV
    Flavia Valtorta

    Vita-Salute San Raffaele University, Italy

    3 publications · 265 citations

    3

    h-index

1–5 of 403

Institutions

164

  1. Inserm

    Paris, France

    5 h-index

    14 publications

    1.1K citations

  2. Baylor College of Medicine

    Houston, United States

    5 h-index

    12 publications

    435 citations

  3. Italian Institute of Technology

    Genoa, Italy

    4 h-index

    31 publications

    2.2K citations

  4. University of Genoa

    Genoa, Italy

    4 h-index

    24 publications

    1.7K citations

  5. University of Toronto

    Toronto, Canada

    3 h-index

    5 publications

    195 citations

  6. University of Alabama at Birmingham

    Birmingham, United States

    3 h-index

    8 publications

    918 citations

  7. Harvard University

    Cambridge, United States

    3 h-index

    7 publications

    1.8K citations

  8. Vita-Salute San Raffaele University

    Milan, Italy

    3 h-index

    7 publications

    685 citations

1–8 of 164

Venues

  1. Neuroscience

    6 publications · 229 citations

    6

    h-index

  2. Brain Research

    4 publications · 73 citations

    4

    h-index

  3. Epilepsy Research

    4 publications · 314 citations

    4

    h-index

  4. Cerebral Cortex

    4 publications · 314 citations

    4

    h-index

  5. Neurobiology of Disease

    4 publications · 133 citations

    4

    h-index

1–5