Concepedia

Synaptic Gain Modulation

Synaptic Gain Modulation is a neurophysiological mechanism that adjusts the sensitivity of postsynaptic neurons to incoming synaptic inputs by multiplicatively scaling their input-output relationship, thereby regulating the efficacy of synaptic integration without altering the basic pattern of synaptic connectivity.

99

Publications

11.1K

Citations

308

Authors

159

Institutions

Publications per year

2017–2026

24

Parents

Publications

99

Synaptic Depression and Cortical Gain Control

L. F. Abbott, Juan A. Varela, Kamal Sen et al. · Science · 1997 · 1.7K citations

, , +17

Gain Modulation from Background Synaptic Input

Frances S. Chance, L. F. Abbott, Alex D. Reyes · Neuron · 2002 · 1K citations · Full text

, , +12

Tonic Synaptic Inhibition Modulates Neuronal Output Pattern and Spatiotemporal Synaptic Integration

Michael Häusser, Beverley A. Clark · Neuron · 1997 · 651 citations · Full text

, , +12

Shunting Inhibition Modulates Neuronal Gain during Synaptic Excitation

Simon J. Mitchell, R. Angus Silver · Neuron · 2003 · 616 citations · Full text

, , +13

Top-down Dendritic Input Increases the Gain of Layer 5 Pyramidal Neurons

Matthew E. Larkum · Cerebral Cortex · 2004 · 386 citations · Full text

, , +16

1–5 of 99

Authors

308

  1. KF
    Karl Friston

    University College London, United Kingdom

    5 publications · 572 citations

    5

    h-index

  2. LF
    L. F. Abbott

    Columbia University, United States

    3 publications · 1.4K citations

    3

    h-index

  3. CS
    Cooper Smout

    The University of Queensland, Australia

    2 publications · 142 citations

    2

    h-index

  4. JE
    John E. Misiaszek

    University of Alberta, Canada

    2 publications · 93 citations

    2

    h-index

  5. RW
    Rainer W. Friedrich

    Friedrich Miescher Institute, Switzerland

    2 publications · 27 citations

    2

    h-index

1–5 of 308

Institutions

159

  1. University College London

    London, United Kingdom

    10 h-index

    28 publications

    4.5K citations

  2. New York University

    New York, United States

    7 h-index

    25 publications

    4.8K citations

  3. Wellcome Centre for Human Neuroimaging

    London, United Kingdom

    6 h-index

    15 publications

    2.5K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    10 publications

    382 citations

  5. Brandeis University

    Waltham, United States

    4 h-index

    11 publications

    8.6K citations

  6. University of Pittsburgh

    Pittsburgh, United States

    4 h-index

    11 publications

    390 citations

  7. The University of Queensland

    Brisbane, Australia

    3 h-index

    11 publications

    625 citations

  8. The University of Tokyo

    Tokyo, Japan

    3 h-index

    3 publications

    494 citations

1–8 of 159

Venues

  1. Journal of Neuroscience

    16 publications · 1.4K citations

    15

    h-index

  2. Journal of Neurophysiology

    JN · 8 publications · 478 citations

    8

    h-index

  3. Neuron

    6 publications · 3K citations

    6

    h-index

  4. PLoS Computational Biology

    4 publications · 267 citations

    4

    h-index

  5. Journal of Computational Neuroscience

    3 publications · 83 citations

    3

    h-index

1–5