Concepedia

Synaptic Cleft Dynamics

Synaptic Cleft Dynamics is a theoretical construct that characterizes the spatiotemporal changes in neurotransmitter concentration, ionic flux, and molecular diffusion within the extracellular microenvironment of the synaptic cleft, governing the efficiency and precision of synaptic transmission.

64

Publications

4.3K

Citations

234

Authors

113

Institutions

Publications per year

2017–2026

10

Parents

Publications

64

Transmitter timecourse in the synaptic cleft: its role in central synaptic function

John D. Clements · Trends in Neurosciences · 1996 · 607 citations

, , +16

Proteomic Analysis of Unbounded Cellular Compartments: Synaptic Clefts

Ken H. Loh, Philipp Stawski, Austin S. Draycott et al. · Cell · 2016 · 437 citations · Full text

, , +16

Postfusional regulation of cleft glutamate concentration during LTP at ‘silent synapses’

Sukwoo Choi, Jürgen Klingauf, Richard W. Tsien · Nature Neuroscience · 2000 · 246 citations

, , +16

Modulation of Glutamate Mobility Reveals the Mechanism Underlying Slow-Rising AMPAR EPSCs and the Diffusion Coefficient in the Synaptic Cleft

Thomas A. Nielsen, David A. DiGregorio, R. Angus Silver · Neuron · 2004 · 218 citations · Full text

, , +17

Glutamate translocation of the neuronal glutamate transporter EAAC1 occurs within milliseconds

Christof Grewer, Natalie Watzke, Thomas Rauen · Proceedings of the National Academy of Sciences · 2000 · 176 citations

, , +17

1–5 of 64

Authors

234

  1. LP
    Leonid P. Savtchenko

    University College London, United Kingdom

    3 publications · 65 citations

    3

    h-index

  2. DA
    Dmitri A. Rusakov

    University College London, United Kingdom

    2 publications · 42 citations

    2

    h-index

  3. RA
    R. Angus Silver

    University College London, United Kingdom

    2 publications · 385 citations

    2

    h-index

  4. MG
    M.I. Glavinoviċ

    McGill University, Canada

    2 publications · 41 citations

    2

    h-index

  5. WB
    Werner Baumgärtner

    RWTH Aachen University, Germany

    2 publications · 32 citations

    2

    h-index

1–5 of 234

Institutions

113

  1. University College London

    London, United Kingdom

    6 h-index

    17 publications

    1.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    10 publications

    268 citations

  3. Harvard University

    Cambridge, United States

    3 h-index

    10 publications

    1.8K citations

  4. RWTH Aachen University

    Aachen, Germany

    2 h-index

    5 publications

    74 citations

  5. National Hospital for Neurology and Neurosurgery

    London, United Kingdom

    2 h-index

    4 publications

    84 citations

  6. Oles Honchar Dnipro National University

    Dnipro, Ukraine

    2 h-index

    4 publications

    96 citations

  7. University of Naples Federico II

    Naples, Italy

    2 h-index

    4 publications

    162 citations

  8. Memorial University of Newfoundland

    St. John's, Canada

    2 h-index

    11 publications

    346 citations

1–8 of 113

Venues

  1. The Journal of Physiology

    5 publications · 425 citations

    5

    h-index

  2. Journal of Neuroscience

    4 publications · 252 citations

    4

    h-index

  3. Journal of Neurophysiology

    JN · 3 publications · 212 citations

    3

    h-index

  4. Synapse

    3 publications · 46 citations

    3

    h-index

  5. Biophysical Journal

    3 publications · 183 citations

    3

    h-index

1–5