Concepedia

Surface Immobilization Effects

Surface Immobilization Effects is a methodological consideration in ligand binding kinetics that refers to the alteration of binding kinetics due to the attachment of biomolecules to a solid surface, leading to changes in molecular orientation, accessibility, or mobility compared to solution-phase interactions.

238

Publications

10.5K

Citations

1.1K

Authors

356

Institutions

Publications per year

2017–2026

42

Parents

Publications

238

Surface topography of histidine residues: a facile probe by immobilized metal ion affinity chromatography.

Esmat Sayeda Hemdan, Yajie Zhao, E. Sulkowski et al. · Proceedings of the National Academy of Sciences · 1989 · 277 citations · Full text

, , +17

Proteins Immobilized at the Galleries of Layered α-Zirconium Phosphate:  Structure and Activity Studies

Challa V. Kumar, Anita Chaudhari · Journal of the American Chemical Society · 2000 · 267 citations

, , +17

Kinetics of ligand binding to receptor immobilized in a polymer matrix, as detected with an evanescent wave biosensor. I. A computer simulation of the influence of mass transport

Peter Schuck · Biophysical Journal · 1996 · 234 citations

, , +17

Real-Time Competitive Kinetic Analysis of Interactions between Low-Molecular-Weight Ligands in Solution and Surface-Immobilized Receptors

Robert Karlsson · Analytical Biochemistry · 1994 · 209 citations

, , +15

Immobilized RGD peptides on surface-grafted dextran promote biospecific cell attachment

Stephen P. Massia, John Stark · Journal of Biomedical Materials Research · 2001 · 206 citations

, , +17

1–5 of 238

Authors

1.1K

  1. ZC
    Zhan Chen

    University of Michigan, United States

    6 publications · 205 citations

    6

    h-index

  2. XH
    Xiaofeng Han

    Southeast University, China

    5 publications · 154 citations

    5

    h-index

  3. CL
    Charles L. Brooks

    University of Michigan, United States

    4 publications · 142 citations

    4

    h-index

  4. SO
    Shinobu Oda

    Kansai Paint (Japan), Japan

    3 publications · 77 citations

    3

    h-index

  5. ZW
    Zunliang Wang

    Southeast University, China

    3 publications · 91 citations

    3

    h-index

1–5 of 1.1K

Institutions

356

  1. University of Michigan

    Ann Arbor, United States

    6 h-index

    30 publications

    1.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    5 h-index

    9 publications

    447 citations

  3. ETH Zurich

    Zurich, Switzerland

    4 h-index

    12 publications

    375 citations

  4. Southeast University

    Nanjing, China

    4 h-index

    11 publications

    294 citations

  5. Texas Children's Hospital

    Houston, United States

    3 h-index

    4 publications

    217 citations

  6. University of Utah

    Salt Lake City, United States

    3 h-index

    9 publications

    420 citations

  7. University of Illinois Urbana-Champaign

    Urbana, United States

    3 h-index

    7 publications

    359 citations

  8. University of California, Berkeley

    Berkeley, United States

    3 h-index

    7 publications

    275 citations

1–8 of 356

Venues

  1. Analytical Chemistry

    15 publications · 948 citations

    14

    h-index

  2. Colloids and Surfaces B Biointerfaces

    11 publications · 366 citations

    11

    h-index

  3. Langmuir

    11 publications · 396 citations

    10

    h-index

  4. Journal of the American Chemical Society

    JACS · 10 publications · 739 citations

    10

    h-index

  5. Biomaterials

    7 publications · 487 citations

    7

    h-index

1–5