Concepedia

Suppository Bioavailability

Suppository Bioavailability is the fraction and rate at which the active pharmaceutical ingredient administered via a rectal suppository is absorbed into the systemic circulation and becomes available at the site of action, distinguishing it from other routes of administration by its dependence on rectal mucosal absorption and avoidance of hepatic first-pass metabolism.

100

Publications

2.8K

Citations

408

Authors

120

Institutions

Publications per year

2017–2026

4

Parents

Publications

100

In situ gelling and mucoadhesive liquid suppository containing acetaminophen: enhanced bioavailability

Han‐Gon Choi, Yu‐Kyoung Oh, Chong‐Kook Kim · International Journal of Pharmaceutics · 1998 · 185 citations

, , +15

Increased bioavailability of propranolol in rats by retaining thermally gelling liquid suppositories in the rectum

Jei‐Man Ryu, Suk-Jae Chung, Min-Hwa Lee et al. · Journal of Controlled Release · 1999 · 130 citations

, , +12

Mechanism of Absorption Enhancement in Humans After Rectal Administration of Ampicillin in Suppositories Containing Sodium Caprate

Tuulikki Lindmark, Johan D. Söderholm, Gunnar Olaison et al. · Pharmaceutical Research · 1997 · 101 citations

, , +16

Development of a thermo-reversible insulin liquid suppository with bioavailability enhancement

Mi Ok Yun · International Journal of Pharmaceutics · 1999 · 86 citations

, , +12

Rectal absorption of insulin suppositories in rabbits

Kunihide Ichikawa, Isao Oh Ata, Mitsuo Mitomi et al. · Journal of Pharmacy and Pharmacology · 1980 · 73 citations

, , +15

1–5 of 100

Authors

408

  1. KU
    Kaneto Uekama

    Kumamoto University, Japan

    8 publications · 218 citations

    8

    h-index

  2. TI
    Tetsumi Irie

    Kumamoto University, Japan

    6 publications · 163 citations

    6

    h-index

  3. TN
    Toshiaki Nishihata

    University of Kansas, United States

    5 publications · 94 citations

    5

    h-index

  4. CK
    Chong‐Kook Kim

    Seoul National University, South Korea

    4 publications · 370 citations

    4

    h-index

  5. HA
    Hidetoshi Arima

    Kumamoto University, Japan

    3 publications · 69 citations

    3

    h-index

1–5 of 408

Institutions

120

  1. The University of Osaka

    Osaka, Japan

    6 h-index

    17 publications

    498 citations

  2. Kumamoto University

    Kumamoto, Japan

    6 h-index

    21 publications

    645 citations

  3. Seoul National University

    Seoul, South Korea

    5 h-index

    15 publications

    1.5K citations

  4. Al-Azhar University

    Cairo, Egypt

    3 h-index

    10 publications

    270 citations

  5. Karolinska Institutet

    Stockholm, Sweden

    3 h-index

    8 publications

    272 citations

  6. Osaka Police Hospital

    Osaka, Japan

    2 h-index

    7 publications

    247 citations

  7. Obafemi Awolowo University

    Ile-Ife, Nigeria

    2 h-index

    6 publications

    87 citations

  8. University of Szeged

    Szeged, Hungary

    2 h-index

    6 publications

    136 citations

1–8 of 120

Venues

  1. International Journal of Pharmaceutics

    17 publications · 546 citations

    14

    h-index

  2. PubMed

    Repository · 13 publications · 246 citations

    11

    h-index

  3. Journal of Pharmaceutical Sciences

    8 publications · 237 citations

    8

    h-index

  4. Chemical and Pharmaceutical Bulletin

    5 publications · 112 citations

    5

    h-index

  5. Biological and Pharmaceutical Bulletin

    5 publications · 77 citations

    5

    h-index

1–5