Concepedia

Supersaturation Maintenance

Supersaturation Maintenance is a methodological framework in pharmaceutical sciences that enables the sustained elevation of drug concentration in solution above its equilibrium solubility by inhibiting precipitation and enhancing kinetic stability.

54

Publications

2.4K

Citations

209

Authors

70

Institutions

Publications per year

2017–2026

27

Parents

Publications

54

Utility of Hydroxypropylmethylcellulose Acetate Succinate (HPMCAS) for Initiation and Maintenance of Drug Supersaturation in the GI Milieu

William Curatolo, James Nightingale, Scott M. Herbig · Pharmaceutical Research · 2009 · 300 citations

, , +14

Maintaining Supersaturation in Aqueous Drug Solutions: Impact of Different Polymers on Induction Times

Grace A. Ilevbare, Haoyu Liu, Kevin J. Edgar et al. · Crystal Growth & Design · 2012 · 241 citations

, , +14

Evolution of Supersaturation of Amorphous Pharmaceuticals: The Effect of Rate of Supersaturation Generation

Dajun Sun, Ping I. Lee · Molecular Pharmaceutics · 2013 · 183 citations

, , +17

Bile Salts as Crystallization Inhibitors of Supersaturated Solutions of Poorly Water-Soluble Compounds

Jie Chen, Laura I. Mosquera-Giraldo, James D. Ormes et al. · Crystal Growth & Design · 2015 · 89 citations

, , +14

Effect of hydrophilic additives on the dissolution and pharmacokinetic properties of itraconazole-enteric polymer hot-melt extruded amorphous solid dispersions

Bo Lang, Sha Liu, James W. McGinity et al. · Drug Development and Industrial Pharmacy · 2015 · 55 citations

, , +17

1–5 of 54

Authors

209

  1. DD
    Dhaval D. Patel

    University of Kentucky, United States

    4 publications · 166 citations

    4

    h-index

  2. BD
    Bradley D. Anderson

    University of Utah, United States

    4 publications · 166 citations

    4

    h-index

  3. KU
    Keisuke Ueda

    Chiba University, Japan

    3 publications · 98 citations

    3

    h-index

  4. LS
    Lynne S. Taylor

    Purdue University West Lafayette, United States

    3 publications · 373 citations

    3

    h-index

  5. KH
    Kenjirou Higashi

    Chiba University, Japan

    3 publications · 98 citations

    3

    h-index

1–5 of 209

Institutions

70

  1. University of Minnesota

    Minneapolis, United States

    5 h-index

    17 publications

    510 citations

  2. Merck & Co., Inc., Rahway, NJ, USA (United States)

    Rahway, United States

    4 h-index

    9 publications

    338 citations

  3. University of Kentucky

    Lexington, United States

    4 h-index

    8 publications

    332 citations

  4. Chiba University

    Chiba, Japan

    3 h-index

    11 publications

    343 citations

  5. Purdue University West Lafayette

    West Lafayette, United States

    3 h-index

    10 publications

    964 citations

  6. Janssen (Belgium)

    Beerse, Belgium

    2 h-index

    7 publications

    257 citations

  7. Boehringer Ingelheim (United States)

    Ridgefield, United States

    2 h-index

    9 publications

    169 citations

  8. Merck KGaA, Darmstadt (Germany)

    Darmstadt, Germany

    2 h-index

    4 publications

    113 citations

1–8 of 70

Venues

  1. Molecular Pharmaceutics

    15 publications · 657 citations

    13

    h-index

  2. Crystal Growth & Design

    6 publications · 474 citations

    6

    h-index

  3. Journal of Pharmaceutical Sciences

    4 publications · 140 citations

    4

    h-index

  4. International Journal of Pharmaceutics

    3 publications · 93 citations

    3

    h-index

  5. Pharmaceutical Development and Technology

    2 publications · 34 citations

    2

    h-index

1–5