Concepedia

Succimer Therapy

Succimer Therapy is a chelation-based antidote therapy that employs oral dimercaptosuccinic acid (succimer) to treat lead and other toxic heavy metal poisonings by selectively forming water-soluble metal–chelate complexes that enhance urinary excretion with minimal loss of essential trace elements.

49

Publications

2.3K

Citations

152

Authors

74

Institutions

Publications per year

2017–2026

0

Variants

Dimercaptosuccinic Acid TherapyDmsa Therapy

Parents

Children

Publications

49

The Effect of Chelation Therapy with Succimer on Neuropsychological Development in Children Exposed to Lead

Walter J. Rogan, Kim N. Dietrich, James H. Ware et al. · New England Journal of Medicine · 2001 · 354 citations · Full text

, , +17

Lead induced oxidative damage and its response to combined administration of α-lipoic acid and succimers in rats

Manisha Pande, S.J.S. Flora · Toxicology · 2002 · 239 citations

, , +14

Effect of Chelation Therapy on the Neuropsychological and Behavioral Development of Lead-Exposed Children After School Entry

Kim N. Dietrich, James H. Ware, M.P. Salganik et al. · PEDIATRICS · 2004 · 202 citations

, , +16

Lead poisoning: case studies

JN Gordon, Alan Taylor, Peter N. Bennett · British Journal of Clinical Pharmacology · 2002 · 121 citations · Full text

, , +15

Chronic arsenic poisoning in the rat: treatment with combined administration of succimers and an antioxidant

G. M. Kannan, S.J.S. Flora · Ecotoxicology and Environmental Safety · 2003 · 88 citations

, , +14

1–5 of 49

Authors

152

  1. DR
    Donald R. Smith

    University of California, Santa Cruz, United States

    8 publications · 298 citations

    8

    h-index

  2. WJ
    Walter J. Rogan

    National Institute of Environmental Health Sciences, United States

    6 publications · 624 citations

    6

    h-index

  3. KN
    Kim N. Dietrich

    University of Cincinnati Medical Center, United States

    4 publications · 614 citations

    4

    h-index

  4. GG
    George G. Rhoads

    Rutgers, The State University of New Jersey, United States

    4 publications · 585 citations

    4

    h-index

  5. MS
    M.P. Salganik

    Harvard University, United States

    4 publications · 585 citations

    4

    h-index

1–5 of 152

Institutions

74

  1. University of California, Santa Cruz

    Santa Cruz, United States

    7 h-index

    7 publications

    254 citations

  2. National Institute of Environmental Health Sciences

    Durham, United States

    5 h-index

    5 publications

    610 citations

  3. Harvard University

    Cambridge, United States

    5 h-index

    5 publications

    600 citations

  4. Centers for Disease Control and Prevention

    Atlanta, United States

    4 h-index

    4 publications

    288 citations

  5. University of Cincinnati Medical Center

    Cincinnati, United States

    4 h-index

    4 publications

    272 citations

  6. Cornell University

    Ithaca, United States

    4 h-index

    4 publications

    158 citations

  7. Children's Hospital of Philadelphia

    Philadelphia, United States

    3 h-index

    3 publications

    583 citations

  8. Environmental and Occupational Health Sciences Institute

    Piscataway, United States

    3 h-index

    3 publications

    571 citations

1–8 of 74

Venues

  1. Journal of Toxicology Clinical Toxicology

    5 publications · 167 citations

    5

    h-index

  2. Environmental Health Perspectives

    EHP · 5 publications · 137 citations

    5

    h-index

  3. PubMed

    Repository · 4 publications · 120 citations

    4

    h-index

  4. Environmental Research

    2 publications · 75 citations

    2

    h-index

  5. Toxicology and Applied Pharmacology

    TAAP · 2 publications · 72 citations

    2

    h-index

1–5