Concepedia

Subunit Cooperativity

Subunit Cooperativity is a biochemical phenomenon in which the binding of a ligand to one subunit of a multimeric protein influences the ligand-binding affinity of adjacent subunits through conformational changes, thereby enabling coordinated functional responses within the quaternary structure.

452

Publications

21.2K

Citations

1.5K

Authors

430

Institutions

Publications per year

2017–2026

25

Parents

Publications

452

Change in the Presence of Residual Fit: Can Competing Frames Coexist?

Clark Gilbert · Organization Science · 2006 · 406 citations

, , +16

NEGATIVE COOPERATIVITY IN REGULATORY ENZYMES

Alexander Levitzki, Daniel E. Koshland · Proceedings of the National Academy of Sciences · 1969 · 388 citations · Full text

, , +17

The I-II Loop of the Ca 2+ Channel α 1 Subunit Contains an Endoplasmic Reticulum Retention Signal Antagonized by the β Subunit

Delphine Bichet, Véronique Cornet, Sandrine Geib et al. · Neuron · 2000 · 374 citations · Full text

, , +17

Molecular Code for Cooperativity in Hemoglobin

Gary K. Ackers, Michael L. Doyle, David Myers et al. · Science · 1992 · 321 citations

, , +17

Novel subunit—subunit interactions in the structure of glutamine synthetase

Robert J. Almassy, Cheryl A. Janson, R. Hamlin et al. · Nature · 1986 · 308 citations

, , +14

1–5 of 452

Authors

1.5K

  1. EC
    Emilia Chiancone

    Sapienza University of Rome, Italy

    8 publications · 267 citations

    8

    h-index

  2. DE
    Daniel E. Koshland

    University of California, Berkeley, United States

    7 publications · 832 citations

    7

    h-index

  3. GK
    Gary K. Ackers

    Washington University in St. Louis, United States

    6 publications · 463 citations

    6

    h-index

  4. PD
    Paul D. Boyer

    University of California, Los Angeles, United States

    6 publications · 334 citations

    6

    h-index

  5. QG
    Quentin Gibson

    Cornell University, United States

    4 publications · 244 citations

    4

    h-index

1–5 of 1.5K

Institutions

430

  1. University of California, Berkeley

    Berkeley, United States

    13 h-index

    60 publications

    5.7K citations

  2. National Institutes of Health

    Bethesda, United States

    13 h-index

    44 publications

    1.7K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    31 publications

    2.9K citations

  4. University of California San Diego

    San Diego, United States

    10 h-index

    30 publications

    2.5K citations

  5. Cornell University

    Ithaca, United States

    9 h-index

    26 publications

    1.6K citations

  6. Washington University in St. Louis

    St Louis, United States

    9 h-index

    26 publications

    1.9K citations

  7. Harvard University

    Cambridge, United States

    8 h-index

    24 publications

    1.6K citations

  8. Yale University

    New Haven, United States

    8 h-index

    34 publications

    1.9K citations

1–8 of 430

Venues

  1. Journal of Biological Chemistry

    JBC · 75 publications · 3.2K citations

    36

    h-index

  2. Biochemistry

    84 publications · 3.5K citations

    36

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 37 publications · 3K citations

    29

    h-index

  4. Archives of Biochemistry and Biophysics

    ABB · 16 publications · 555 citations

    15

    h-index

  5. Journal of Molecular Biology

    JMB · 15 publications · 673 citations

    13

    h-index

1–5