Concepedia

Substrate-induced Activation

Substrate-Induced Activation is an enzyme activation mechanism in which the binding of a substrate molecule to an enzyme induces a conformational change that enhances the enzyme's catalytic activity, thereby distinguishing it from activation mechanisms involving allosteric effectors or covalent modification.

136

Publications

7.2K

Citations

537

Authors

221

Institutions

Publications per year

2017–2026

21

Parents

Publications

136

Substrate-Induced Synthesis And Other Properties Of Benzpyrene Hydroxylase In Rat Liver

Allan H. Conney, E. C. Miller, J. A. Miller · Journal of Biological Chemistry · 1957 · 472 citations · Full text

, , +14

Enantioselective photochemistry through Lewis acid–catalyzed triplet energy transfer

Travis R. Blum, Zachary D. Miller, Desiree M. Bates et al. · Science · 2016 · 418 citations · Full text

, , +16

The Dendrimer Effect in Homogeneous Catalysis

Brett A. Helms, Jean M. J. Fréchet · Advanced Synthesis & Catalysis · 2006 · 360 citations

, , +17

Structure and Mechanism of the Lantibiotic Cyclase Involved in Nisin Biosynthesis

John‐Paul J. Yu, J.S. Brunzelle, Gert N. Moll et al. · Science · 2006 · 306 citations

, , +14

Substrate-induced transmembrane signaling in the cobalamin transporter BtuB

David P. Chimento, A. K. Mohanty, Robert J. Kadner et al. · Nature Structural & Molecular Biology · 2003 · 289 citations

, , +13

1–5 of 136

Authors

537

  1. FJ
    Frank Jordan

    Rutgers, The State University of New Jersey, United States

    5 publications · 110 citations

    5

    h-index

  2. PM
    Patrick Masson

    Service de Santé des Armées, France

    4 publications · 267 citations

    4

    h-index

  3. WF
    William Furey

    University of Pittsburgh, United States

    3 publications · 104 citations

    3

    h-index

  4. IB
    Irina Baburina

    Saladax Biomedical (United States), United States

    3 publications · 106 citations

    3

    h-index

  5. HL
    Haijuan Li

    Changchun Institute of Applied Chemistry, China

    3 publications · 67 citations

    3

    h-index

1–5 of 537

Institutions

221

  1. Rutgers, The State University of New Jersey

    New Brunswick, United States

    7 h-index

    26 publications

    747 citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    15 publications

    690 citations

  3. Freie Universität Berlin

    Berlin, Germany

    3 h-index

    10 publications

    184 citations

  4. Service de Santé des Armées

    Metz, France

    3 h-index

    9 publications

    668 citations

  5. Universidade Federal de Minas Gerais

    Belo Horizonte, Brazil

    3 h-index

    17 publications

    325 citations

  6. Harvard University

    Cambridge, United States

    3 h-index

    8 publications

    344 citations

  7. University of Virginia

    Charlottesville, United States

    2 h-index

    7 publications

    1.4K citations

  8. University of California San Diego

    San Diego, United States

    2 h-index

    4 publications

    220 citations

1–8 of 221

Venues

  1. Biochemistry

    16 publications · 568 citations

    16

    h-index

  2. Journal of Biological Chemistry

    JBC · 13 publications · 1.1K citations

    13

    h-index

  3. Biochemical Journal

    BJ · 6 publications · 233 citations

    6

    h-index

  4. European Journal of Biochemistry

    EJB · 5 publications · 262 citations

    5

    h-index

  5. Angewandte Chemie International Edition

    4 publications · 167 citations

    4

    h-index

1–5