Concepedia

Substrate Translocation

Substrate Translocation is a molecular transport mechanism, specifically the selective transmembrane movement of cytosolic proteins bearing a KFERQ-like motif into the lysosomal lumen mediated by the chaperone Hsc70 and the lysosomal receptor LAMP2A during chaperone-mediated autophagy.

282

Publications

19.9K

Citations

1.4K

Authors

483

Institutions

Publications per year

2017–2026

65

Parents

Publications

282

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

Yukiko Kabeya, Noboru Mizushima, Akitsugu Yamamoto et al. · Journal of Cell Science · 2004 · 1.4K citations

, , +15

Structure and Mechanism of the Glycerol-3-Phosphate Transporter from <i>Escherichia coli</i>

Yafei Huang, M. Joanne Lemieux, Jinmei Song et al. · Science · 2003 · 1K citations

, , +16

The Chaperone-Mediated Autophagy Receptor Organizes in Dynamic Protein Complexes at the Lysosomal Membrane

Urmi Bandyopadhyay, Susmita Kaushik, Lyuba Varticovski et al. · Molecular and Cellular Biology · 2008 · 539 citations · Full text

, , +17

Thermotolerance Requires Refolding of Aggregated Proteins by Substrate Translocation through the Central Pore of ClpB

Jimena Weibezahn, Peter Tessarz, Christian Schlieker et al. · Cell · 2004 · 469 citations · Full text

, , +17

Multiple Ionic Conductances of the Human Dopamine Transporter: The Actions of Dopamine and Psychostimulants

Mark S. Sonders, Si-Jia Zhu, Nancy R. Zahniser et al. · Journal of Neuroscience · 1997 · 456 citations · Full text

, , +17

1–5 of 282

Authors

1.4K

  1. DW
    Da‐Neng Wang

    New York University, United States

    7 publications · 1.2K citations

    7

    h-index

  2. AM
    Ana María Cuervo

    Albert Einstein College of Medicine, United States

    6 publications · 1.2K citations

    6

    h-index

  3. SA
    Stephen A. Baldwin

    University of Leeds, United Kingdom

    4 publications · 123 citations

    4

    h-index

  4. GH
    Gerhard Hummer

    Max Planck Institute of Biophysics, Germany

    4 publications · 153 citations

    4

    h-index

  5. CG
    Christof Grewer

    Binghamton University, United States

    4 publications · 126 citations

    4

    h-index

1–5 of 1.4K

Institutions

483

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    13 h-index

    31 publications

    3.8K citations

  2. Goethe University Frankfurt

    Frankfurt am Main, Germany

    8 h-index

    30 publications

    1.6K citations

  3. New York University

    New York, United States

    8 h-index

    32 publications

    5.9K citations

  4. National Institutes of Health

    Bethesda, United States

    7 h-index

    36 publications

    3K citations

  5. Harvard University

    Cambridge, United States

    7 h-index

    22 publications

    1.8K citations

  6. University of California, Berkeley

    Berkeley, United States

    7 h-index

    19 publications

    1.2K citations

  7. Scripps Research Institute

    San Diego, United States

    7 h-index

    25 publications

    1.4K citations

  8. Max Planck Institute of Biophysics

    Frankfurt am Main, Germany

    7 h-index

    34 publications

    891 citations

1–8 of 483

Venues

  1. Journal of Biological Chemistry

    JBC · 45 publications · 2.6K citations

    27

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 24 publications · 1.9K citations

    21

    h-index

  3. Biochemistry

    14 publications · 433 citations

    13

    h-index

  4. eLife

    12 publications · 569 citations

    12

    h-index

  5. Nature Communications

    10 publications · 678 citations

    10

    h-index

1–5